Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 14/20 | 0.68 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.58 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.58 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123011 | 0.92 | GPR132 (0.59) | GPR132CMKLR2CMKLR1ITGB3ITGA2B | |
| SCHEMBL1123016 | 0.83 | RAB9A (0.51) | GPR132RAB9A | |
| SCHEMBL27638089 | 0.83 | GPR132 (0.61) | GPR132CMKLR2CMKLR1ITGB3ITGA2B | |
| SCHEMBL1122721 | 0.82 | PTPN1 (0.68) | GPR132ITGB3ITGA2BPTPN1PPARG | |
| SCHEMBL4645625 | 0.81 | PPARG (0.65) | PPARG | |
| SCHEMBL4645614 | 0.81 | PPARG (0.65) | PPARG | |
| SCHEMBL5936689 | 0.80 | GAA (0.52) | RAB9A | |
| SCHEMBL1123014 | 0.80 | RAB9A (0.47) | RAB9A | |
| SCHEMBL6182299 | 0.79 | GPR132 (0.77) | GPR132CMKLR2CMKLR1ITGB3ITGA2B | |
| SCHEMBL1123033 | 0.79 | GPR132 (0.77) | GPR132ITGB3ITGA2BPTPN1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |