Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123271 | 0.92 | ALOX5 (0.50) | RAB9AALOX5PTGS1PTGS2TSHR | |
| SCHEMBL1123016 | 0.86 | RAB9A (0.51) | RAB9AALOX5F10GAATSHR | |
| SCHEMBL5936689 | 0.83 | GAA (0.52) | RAB9AF10GAATSHRSLC2A1 | |
| SCHEMBL1122704 | 0.80 | GPR132 (0.68) | RAB9A | |
| SCHEMBL1123270 | 0.77 | ALOX5 (0.53) | RAB9AALOX5PTGS1PTGS2MAOB | |
| SCHEMBL1123012 | 0.75 | RAB9A (0.45) | RAB9AF10TSHRSLC2A1MMP2 | |
| SCHEMBL8967341 | 0.74 | SLC2A1 (0.54) | F10TSHRSLC2A1SLC2A4NPC1 | |
| Hydrochloric Acid SCHEMBL8967290 | 0.73 | SLC2A1 (0.53) | F10TSHRSLC2A1SLC2A4NPC1 | |
| SCHEMBL1122947 | 0.73 | LPAR1 (0.59) | LPAR1LPAR5 | |
| SCHEMBL1122800 | 0.71 | MAPT (0.62) | RAB9ASLC2A1LPAR1LPAR5HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |