Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1950946 | 0.90 | GLA (0.55) | GLAKMT2AMEN1MAPTP2RX7 | |
| Fluopyram SCHEMBL29353266 | 0.85 | GLA (0.59) | GLAKMT2AMEN1MAPTP2RX7 | |
| Fluopyram SCHEMBL67230 | 0.85 | GLA (0.59) | GLAKMT2AMEN1MAPTP2RX7 | |
| SCHEMBL22809443 | 0.84 | SCN9A (0.58) | KMT2AMEN1P2RX7HDAC6PPARD | |
| SCHEMBL726447 | 0.84 | GLA (0.58) | GLAKMT2AMEN1MAPTP2RX7 | |
| SCHEMBL28357316 | 0.84 | KDM4E (0.62) | GLAKMT2AMEN1MAPTP2RX7 | |
| SCHEMBL2405985 | 0.84 | GLA (0.58) | GLAKMT2AMEN1MAPTP2RX7 | |
| SCHEMBL13213688 | 0.84 | GLA (0.58) | GLAKMT2AMEN1MAPTP2RX7 | |
| SCHEMBL14686410 | 0.84 | MAPT (0.53) | GLAKMT2AMEN1MAPTP2RX7 | |
| SCHEMBL4796623 | 0.83 | KMT2A (0.51) | GLAKMT2AMEN1MAPTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597252-B1 | PYRIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | BAYER SAS (FR) | 2011-02-09 | — | — | EP | disclosed |
| US-7754741-B2 | Pyridine derivatives as fungicidal compounds | BAYER CROPSCIENCE S.A. (FR) | 2010-07-13 | — | — | US | disclosed |
| US-7754741-B2 | Pyridine derivatives as fungicidal compounds | BAYER CROPSCIENCE S.A. (FR) | 2010-07-13 | — | — | US | disclosed |
| US-7754741-B2 | Pyridine derivatives as fungicidal compounds | BAYER CROPSCIENCE S.A. (FR) | 2010-07-13 | — | — | US | disclosed |
| US-20060052366-A1 | Pyridine derivatives as fungicidal compounds | BAYER SAS (FR) | 2006-03-09 | — | — | US | disclosed |
| EP-1449841-A1 | New fungicidal compounds | Bayer CropScience SA (FR) | 2004-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052366-A1 | Pyridine derivatives as fungicidal compounds | CYP3A7, CYP4B1, CYP4X1 | GLA 695/4885KMT2A 3663/4885MEN1 2071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.