Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluopyram SCHEMBL2847533 | 0.95 | GLA (0.53) | GLAP2RX7MAPTKMT2AMEN1 | |
| SCHEMBL4006228 | 0.93 | GLA (0.53) | GLAP2RX7MAPTKMT2AMEN1 | |
| Fluopyram SCHEMBL29353266 | 0.88 | GLA (0.59) | GLAP2RX7MAPTKMT2AMEN1 | |
| Fluopyram SCHEMBL67230 | 0.88 | GLA (0.59) | GLAP2RX7MAPTKMT2AMEN1 | |
| SCHEMBL28357316 | 0.87 | KDM4E (0.62) | GLAP2RX7MAPTKMT2AMEN1 | |
| SCHEMBL2405985 | 0.87 | GLA (0.58) | GLAP2RX7MAPTKMT2AMEN1 | |
| SCHEMBL13213688 | 0.87 | GLA (0.58) | GLAP2RX7MAPTKMT2AMEN1 | |
| SCHEMBL3430049 | 0.85 | P2RX7 (0.48) | P2RX7MAPTKMT2AMEN1POLB | |
| SCHEMBL16363567 | 0.85 | GLA (0.56) | GLAP2RX7MAPTKMT2AMEN1 | |
| SCHEMBL1950946 | 0.85 | GLA (0.55) | GLAP2RX7MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210022341-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-01-28 | — | — | US | claimed |
| US-10827754-B2 | Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the ergosterol biosynthesis | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-11-10 | — | — | US | claimed |
| US-20190014781-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-17 | — | — | US | claimed |
| US-20170000123-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE TRANSPORT OF ELECTRONS OF THE RESPIRATORY CHAIN IN PHYTOPATHOGENIC FUNGAL ORGANISMS | BAYER INTELLECTUAL PROPERTY GMBH | 2017-01-05 | — | — | US | claimed |
| US-20160345579-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-12-01 | — | — | US | claimed |
| US-9445590-B2 | Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the transport of electrons of the respiratory chain in phytopathogenic fungal organisms | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-09-20 | — | — | US | claimed |
| US-8410020-B2 | Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the methionine biosynthesis | BAYER CROPSCIENCE AG (DE) | 2013-04-02 | — | — | US | claimed |
| US-20120184555-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS | BAYER CROPSCIENCE AG (DE) | 2012-07-19 | — | — | US | claimed |
| JP-4794570-B2 | — | — | 2011-10-19 | — | — | JP | claimed |
| JP-4782418-B2 | — | — | 2011-09-28 | — | — | JP | claimed |
| WO-2005077179-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE MELANIN BIOSYNTHISIS | BAYER CROPSCIENCE SA (FR) | 2005-08-25 | — | — | WO | claimed |
| WO-2005077182-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE METHIONINE BIOSYNTHESIS | BAYER CROPSCIENCE SA (FR) | 2005-08-25 | — | — | WO | claimed |
| WO-2005077180-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING MITOSIS AND CELL DIVISION | BAYER CROPSCIENCE SA (FR) | 2005-08-25 | — | — | WO | claimed |
| WO-2005077183-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS | BAYER CROPSCIENCE SA (FR) | 2005-08-25 | — | — | WO | claimed |
| WO-2005077181-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE SPORES GERMINATION OR MYCELIUM GROWTH BY ACTING ON DIFFERENT METABOLIC ROUTES | BAYER CROPSCIENCE SA (FR) | 2005-08-25 | — | — | WO | claimed |
| EP-1563733-A1 | Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting mitosis and cell division | Bayer CropScience S.A. (FR) | 2005-08-17 | — | — | EP | claimed |
| EP-1563731-A1 | Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the ergosterol biosynthesis | Bayer CropScience S.A. (FR) | 2005-08-17 | — | — | EP | claimed |
| EP-1563732-A1 | Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the melanin biosynthesis | Bayer CropScience S.A. (FR) | 2005-08-17 | — | — | EP | claimed |
| EP-1531673-A2 | NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE | Bayer CropScience S.A. (FR) | 2005-05-25 | — | — | EP | claimed |
| WO-2004016088-A2 | NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE | BAYER CROPSCIENCE S.A. (FR) | 2004-02-26 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184555-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS | CYP51A1, ERG28, LSS | GLA 411/4885P2RX7 4488/4885MAPT 3208/4885 |
| US-20190014781-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS | CYP51A1, ERG28, LSS | GLA 411/4885P2RX7 4488/4885MAPT 3208/4885 |
| US-10827754-B2 | Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the ergosterol biosynthesis | CYP51A1, ERG28, LSS | GLA 411/4885P2RX7 4488/4885MAPT 3208/4885 |
| US-20170000123-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE TRANSPORT OF ELECTRONS OF THE RESPIRATORY CHAIN IN PHYTOPATHOGENIC FUNGAL ORGANISMS | SLC25A21, SLC25A1, ETFB | GLA 2234/4885P2RX7 1755/4885MAPT 2088/4885 |
| US-20160345579-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS | CYP51A1, ERG28, CYP17A1 | GLA 581/4885P2RX7 4395/4885MAPT 3571/4885 |
| US-20210022341-A1 | FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS | ERG28, CYP51A1, CYP21A2 | GLA 803/4885P2RX7 2552/4885MAPT 2842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.