Fluopyram

Fluopyram

SCHEMBL67230

O=C(NCCc1ncc(C(F)(F)F)cc1Cl)c1ccccc1C(F)(F)F

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GLA P06280 1/20 0.59
MAPT P10636 2/20 0.52
P2RX7 Q99572 1/20 0.51
KMT2A Q03164 6/20 0.49
MEN1 O00255 5/20 0.47
ALDH1A1 P00352 1/20 0.47
KDM4E B2RXH2 1/20 0.47
POLB P06746 1/20 0.47
GAA P10253 1/20 0.47
CYP1A2 P05177 1/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2C19 P33261 1/20 0.45
NPSR1 Q6W5P4 2/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TP53 P04637 2/20 0.45
PTGES O14684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluopyram SCHEMBL29353266 1.00 GLA (0.59) GLAMAPTP2RX7KMT2AMEN1
Fluopyram SCHEMBL2847533 0.94 GLA (0.53) GLAMAPTP2RX7KMT2AMEN1
SCHEMBL3781264 0.94 GLA (0.54) GLAMAPTP2RX7KMT2AMEN1
SCHEMBL19141018 0.93 GLA (0.51) GLAMAPTP2RX7KMT2AMEN1
SCHEMBL16363567 0.93 GLA (0.56) GLAMAPTP2RX7KMT2AMEN1
SCHEMBL6026868 0.93 GLA (0.53) GLAMAPTP2RX7KMT2AMEN1
Fluopyram SCHEMBL28856454 0.91 GLA (0.50) GLAMAPTP2RX7KMT2AMEN1
Fluopyram SCHEMBL4426432 0.91 GLA (0.50) GLAMAPTP2RX7KMT2AMEN1
SCHEMBL727891 0.90 GLA (0.47) GLAMAPTP2RX7ALDH1A1KDM4E
SCHEMBL19847610 0.89 TP53 (0.48) GLAMAPTP2RX7POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1991 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026088168-A1 STABLE SYNERGISTIC PESTICIDAL COMPOSITION RANI SANGEETA (IN) 2026-04-30 WO claimed
US-20230113346-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION LLC (US) 2023-04-13 US claimed
CN-110291068-B Process for the preparation of 2-pyridylethylcarboxamide derivatives 拜耳农作物科学股份公司 2023-04-11 CN claimed
EP-3558945-B1 PROCESS FOR THE PREPARATION OF A N-[2-(2-PYRIDINYL)ETHYL]CARBOXAMIDE DERIVATIVE BAYER CROPSCIENCE AG (DE) 2021-05-05 EP claimed
US-20210022341-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2021-01-28 US claimed
US-10827754-B2 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the ergosterol biosynthesis BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-11-10 US claimed
US-10807955-B2 Process for the preparation of a 2-pyridylethylcarboxamide derivative BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-10-20 US claimed
CN-111056997-A Synthetic method of benzamide compound 西安近代化学研究所 2020-04-24 CN claimed
WO-2020041040-A1 FUNGICIDAL MIXTURES FOR SOYBEAN DISEASES PIONEER HI-BRED INTERNATIONAL, INC. (US) 2020-02-27 WO claimed
US-20200039937-A1 PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-02-06 US claimed
WO-2005077179-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE MELANIN BIOSYNTHISIS BAYER CROPSCIENCE SA (FR) 2005-08-25 WO claimed
WO-2005077182-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE METHIONINE BIOSYNTHESIS BAYER CROPSCIENCE SA (FR) 2005-08-25 WO claimed
WO-2005077180-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING MITOSIS AND CELL DIVISION BAYER CROPSCIENCE SA (FR) 2005-08-25 WO claimed
WO-2005077181-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE SPORES GERMINATION OR MYCELIUM GROWTH BY ACTING ON DIFFERENT METABOLIC ROUTES BAYER CROPSCIENCE SA (FR) 2005-08-25 WO claimed
WO-2005077901-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE TRANSPORT OF ELECTRONS OF THE RESPIRATORY CHAIN IN PHYTOPATHOGENIC FUNGAL ORGANISMS BAYER CROPSCIENCE SA (FR) 2005-08-25 WO claimed
EP-1563733-A1 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting mitosis and cell division Bayer CropScience S.A. (FR) 2005-08-17 EP claimed
EP-1563732-A1 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the melanin biosynthesis Bayer CropScience S.A. (FR) 2005-08-17 EP claimed
EP-1563731-A1 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the ergosterol biosynthesis Bayer CropScience S.A. (FR) 2005-08-17 EP claimed
EP-1531673-A2 NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE Bayer CropScience S.A. (FR) 2005-05-25 EP claimed
WO-2004016088-A2 NOVEL 2-PYRIDYLETHYLBENZAMIDE DERIVATIVE BAYER CROPSCIENCE S.A. (FR) 2004-02-26 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10807955-B2 Process for the preparation of a 2-pyridylethylcarboxamide derivative CPS1, PLPBP, CYP4F2 GLA 542/4885MAPT 1593/4885P2RX7 2604/4885
US-10827754-B2 Fungicidal composition comprising a pyridylethylbenzamide derivative and a compound capable of inhibiting the ergosterol biosynthesis CYP51A1, ERG28, LSS GLA 411/4885MAPT 3208/4885P2RX7 4488/4885
US-20200039937-A1 PROCESS FOR THE PREPARATION OF A 2-PYRIDYLETHYLCARBOXAMIDE DERIVATIVE CPS1, CYP4F2, PLPBP GLA 618/4885MAPT 1200/4885P2RX7 2495/4885
US-20230113346-A1 FUNGICIDAL COMPOSITIONS BROX, RER1, BLVRB GLA 2485/4885MAPT 1202/4885P2RX7 3094/4885
US-20210022341-A1 FUNGICIDAL COMPOSITION COMPRISING A PYRIDYLETHYLBENZAMIDE DERIVATIVE AND A COMPOUND CAPABLE OF INHIBITING THE ERGOSTEROL BIOSYNTHESIS ERG28, CYP51A1, CYP21A2 GLA 803/4885MAPT 2842/4885P2RX7 2552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.