Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.72 |
| ▸ | HPGD | P15428 | 4/20 | 0.72 |
| ▸ | TSHR | P16473 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.72 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 5/20 | 0.63 |
| ▸ | GFER | P55789 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | ALPL | P05186 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9463878 | 0.84 | ALDH1A1 (1.00) | HSD17B10KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL4772250 | 0.83 | KDM4E (0.74) | HSD17B10KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL15984891 | 0.81 | MCL1 (1.00) | HSD17B10KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL5321909 | 0.81 | KDM4E (0.72) | HSD17B10KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL18232224 | 0.80 | KDM4E (0.70) | HSD17B10KDM4EALDH1A1HPGDTSHR | |
| Trimethylammonium SCHEMBL9481220 | 0.79 | ALDH1A1 (0.88) | HSD17B10KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL11227296 | 0.78 | MCL1 (0.68) | HSD17B10KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL8724340 | 0.78 | GAA (1.00) | HSD17B10KDM4EALDH1A1HPGDMCL1 | |
| SCHEMBL22902127 | 0.77 | ALDH1A1 (0.42) | HSD17B10KDM4EALDH1A1HPGDTSHR | |
| SCHEMBL11195848 | 0.76 | KDM4E (0.74) | HSD17B10KDM4EALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309353-A | ANTI-ALLERGIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| US-4205082-A | ANTI-ALLERGIC AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-05-27 | — | — | US | disclosed |