SCHEMBL8724340

SCHEMBL8724340

Cc1cc(=O)oc2c(N)c(O)ccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 1.00
GFER P55789 1/20 1.00
HSD17B10 Q99714 1/20 1.00
MAOB P27338 8/20 0.71
MCL1 Q07820 3/20 0.71
KDM4E B2RXH2 2/20 0.71
ALDH1A1 P00352 2/20 0.71
MGAM O43451 1/20 0.71
LMNA P02545 1/20 0.71
TP53 P04637 1/20 0.71
CYP3A4 P08684 1/20 0.71
MAPT P10636 1/20 0.71
SI P14410 1/20 0.71
ALOX15 P16050 1/20 0.71
MAPK1 P28482 1/20 0.71
MGAM2 Q2M2H8 1/20 0.71
ERN1 O75460 1/20 0.65
MAOA P21397 6/20 0.63
ERAP1 Q9NZ08 2/20 0.53
KMT2A Q03164 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4187220 0.83 MAOB (1.00) GAAGFERHSD17B10MAOBMCL1
4-Methyldaphnetin SCHEMBL29671915 0.83 MCL1 (1.00) GAAGFERHSD17B10MAOBMCL1
4-Methyldaphnetin SCHEMBL1065373 0.83 MCL1 (1.00) GAAGFERHSD17B10MAOBMCL1
SCHEMBL10627951 0.80 MAOB (0.71) GAAGFERHSD17B10MAOBMCL1
SCHEMBL9464086 0.80 MAOB (0.71) GAAGFERHSD17B10MAOBMCL1
SCHEMBL23143160 0.80 MAOB (0.71) GAAGFERHSD17B10MAOBMCL1
SCHEMBL28542436 0.80 ERN1 (0.78) GAAGFERHSD17B10MAOBMCL1
SCHEMBL14398970 0.79 ERN1 (1.00) GAAGFERHSD17B10MAOBMCL1
SCHEMBL18155873 0.78 KDM4E (0.67) GAAGFERHSD17B10MAOBMCL1
SCHEMBL31454902 0.78 MAOB (0.67) GAAGFERHSD17B10MAOBMCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023094734-A1 LIGANDS SPECIFICALLY TARGETING VESICULAR GLUTAMATE TRANSPORTERS FOR SUPER-RESOLUTION IMAGING Sorbonne Université (FR) 2023-06-01 WO disclosed
US-20150306237-A1 HYALURONIC ACID-ANTIOXIDANT CONJUGATES AND THEIR USES UNIVERSITY OF GENEVA (CH) 2015-10-29 US disclosed
US-20150306237-A1 HYALURONIC ACID-ANTIOXIDANT CONJUGATES AND THEIR USES UNIVERSITY OF GENEVA (CH) 2015-10-29 US disclosed
US-5789138-A Optical recording medium and method of producing the same RICOH COMPANY, LTD. (JP) 1998-08-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150306237-A1 HYALURONIC ACID-ANTIOXIDANT CONJUGATES AND THEIR USES CD44, HAO2, LPO GAA 386/4885GFER 180/4885HSD17B10 405/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.