Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | PDE2A | O00408 | 4/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.53 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.38 |
| ▸ | CDC25B | P30305 | 5/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11121799 | 0.85 | PDE2A (0.59) | HTR1APDE2ABCHEHSPA5PTPN1 | |
| SCHEMBL11123182 | 0.83 | HTR1A (0.55) | HTR1APDE2ABCHEPTPN1CDC25B | |
| SCHEMBL11126005 | 0.79 | PDE2A (0.56) | HTR1APDE2ABCHEHSPA5CA1 | |
| SCHEMBL6306348 | 0.79 | PDE2A (0.61) | HTR1APDE2ABCHEHSPA5PTPN1 | |
| SCHEMBL6306351 | 0.79 | PDE2A (0.61) | HTR1APDE2ABCHEHSPA5PTPN1 | |
| SCHEMBL8764444 | 0.78 | PDE2A (0.70) | HTR1APDE2ABCHEADORA2AADORA2B | |
| SCHEMBL750344 | 0.77 | PDE2A (0.72) | HTR1APDE2ABCHEADORA2AADORA2B | |
| SCHEMBL5961364 | 0.77 | PDE2A (0.64) | HTR1APDE2ABCHEHSPA5ADORA2A | |
| SCHEMBL11427985 | 0.77 | PDE2A (0.64) | HTR1APDE2ABCHEHSPA5ADORA2A | |
| SCHEMBL6293320 | 0.77 | HTR1A (0.56) | HTR1APDE2ABCHEPTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4315000-A | β-D-Arabinofuranosylimidazo(4,5-c)pyridine compounds and methods for their production | WARNER-LAMBERT COMPANY (US) | 1982-02-09 | — | — | US | disclosed |
| EP-0043722-A1 | Beta-D-Arabinofuranosylimidazo (4,5-c)pyridine compounds and processes for their production | WARNER-LAMBERT COMPANY (US) | 1982-01-13 | — | — | EP | disclosed |