Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | AHCY | P23526 | 2/20 | 0.54 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.50 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.50 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.49 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.47 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.47 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11427985 | 1.00 | PDE2A (0.64) | PDE2AHTR1AAHCYHSPA5ADORA1 | |
| SCHEMBL14429057 | 0.94 | PDE2A (0.59) | PDE2AHTR1AAHCYHSPA5ADORA1 | |
| SCHEMBL14429257 | 0.92 | PDE2A (0.59) | PDE2AAHCYHSPA5ADORA1P2RY12 | |
| SCHEMBL14429024 | 0.92 | PDE2A (0.71) | PDE2AHTR1AAHCYHSPA5ADORA1 | |
| SCHEMBL14428965 | 0.92 | PDE2A (0.59) | PDE2AAHCYHSPA5ADORA1P2RY12 | |
| SCHEMBL20096659 | 0.89 | AHCY (0.55) | PDE2AAHCYADORA1P2RY12NT5E | |
| SCHEMBL8764444 | 0.87 | PDE2A (0.70) | PDE2AHTR1AADORA1NT5EBCHE | |
| SCHEMBL750344 | 0.87 | PDE2A (0.72) | PDE2AHTR1AADORA1NT5EBCHE | |
| SCHEMBL622588 | 0.85 | ADORA1 (0.69) | PDE2AAHCYHSPA5ADORA1DOT1L | |
| SCHEMBL7906337 | 0.85 | HSPA5 (0.62) | PDE2AAHCYHSPA5ADORA1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1283211-B1 | L-Nucleosides for the treatment of hepatitis B-virus and Epstein-barr virus | UNIV GEORGIA RES FOUND (US) | 2006-06-07 | — | — | EP | disclosed |
| EP-0748330-B1 | L-NUCLEOSIDES FOR THE TREATMENT OF HEPATITIS B-VIRUS AND EPSTEIN-BAR VIRUS | UNIV GEORGIA RES FOUND (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-1283211-A2 | L-Nucleosides for the treatment of hepatitis B-virus and Epstein-barr virus | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2003-02-12 | — | — | EP | disclosed |
| US-5808040-A | VIRICIDES | YALE UNIVERSITY (US) | 1998-09-15 | — | — | US | disclosed |
| US-5753789-A | Oligonucleotides containing L-nucleosides | YALE UNIVERSITY (US) | 1998-05-19 | — | — | US | disclosed |
| US-5567688-A | ADMINISTERING SPECIFIED ENANTIOMORPH TO HUMAN INFECTED WITH HEPATITIS B VIRUS | UNIV. OF GA RESEARCH FOUNDATION (US) | 1996-10-22 | — | — | US | disclosed |
| US-5565438-A | L-nucleosides for the treatment of epstein-bar virus | UNIVERSITY OF GA RESEARCH FOUNDATION (US) | 1996-10-15 | — | — | US | disclosed |