Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 7/20 | 0.70 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.52 |
| ▸ | HINT1 | P49773 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL750344 | 0.91 | PDE2A (0.72) | PDE2AHTR1AADORA2AADORA2BBCHE | |
| SCHEMBL5961364 | 0.87 | PDE2A (0.64) | PDE2AHTR1AADORA2AADORA2BBCHE | |
| SCHEMBL11427985 | 0.87 | PDE2A (0.64) | PDE2AHTR1AADORA2AADORA2BBCHE | |
| SCHEMBL11121799 | 0.84 | PDE2A (0.59) | PDE2AHTR1AADORA2AADORA2BBCHE | |
| SCHEMBL11420439 | 0.83 | PDE2A (0.61) | PDE2AHTR1AADORA2AADORA2BBCHE | |
| SCHEMBL6306348 | 0.83 | PDE2A (0.61) | PDE2AHTR1AADORA2AADORA2BBCHE | |
| SCHEMBL6306351 | 0.83 | PDE2A (0.61) | PDE2AHTR1AADORA2AADORA2BBCHE | |
| SCHEMBL9097705 | 0.83 | PDE2A (0.70) | PDE2AHTR1ABCHEADORA3NT5E | |
| SCHEMBL11126005 | 0.82 | PDE2A (0.56) | PDE2AHTR1AADORA2AADORA2BBCHE | |
| SCHEMBL14429057 | 0.81 | PDE2A (0.59) | PDE2AHTR1ABCHEADORA3ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6065281-A | — | — | None | — | — | JP | disclosed |
| JP-7138280-A | — | — | None | — | — | JP | disclosed |
| EP-0461407-B1 | Improved process for the preparation of 2-amino(2,3,5-tri-O-benzyl-beta-D-arabinofuranosyl)adenine | ASH STEVENS INC (US) | 1997-07-30 | — | — | EP | disclosed |
| JP-H07138280-A | PRODUCTION OF 9-BETA-D-ARABINOFURANOSYL-2-FLUOROADENINE | ASH STEVENS INC | 1995-05-30 | — | — | JP | disclosed |
| JP-H0665281-A | IMPROVEMENT OF PREPARATION OF 2-AMINO(2,3,5-TRI-O-BENZYL-BETA-D-ARABINOFURANOSYL)ADENINE | ASH STEVENS INC | 1994-03-08 | — | — | JP | disclosed |
| US-5180824-A | 6-AZIDO-2-FLUOROPURINE, USEFUL IN THE SYNTHESIS OF NUCLEOSIDES | BERLEX BIOSCIENCES INC. (US) | 1993-01-19 | — | — | US | disclosed |
| US-5110919-A | Economical preparation of nucleosides | ASH STEVENS, INC. (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0461407-A1 | Improved process for the preparation of 2-amino(2,3,5-tri-O-benzyl-beta-D-arabinofuranosyl)adenine | ASH STEVENS, INC. (US) | 1991-12-18 | — | — | EP | disclosed |
| US-4210745-A | Procedure for the preparation of 9-β-D-arabinofuranosyl-2-fluoroadenine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1980-07-01 | — | — | US | disclosed |
| US-4188378-A | Anticancer and antiviral activity of 9-β-D-arabinofuranosyl-2-fluoroadenine | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH, EDUCATION AND WELFARE (US) | 1980-02-12 | — | — | US | disclosed |
| US-4081534-A | Amino purine nucleosides as autoimmune suppressant agents | BURROUGHS WELLCOME CO. (US) | 1978-03-28 | — | — | US | disclosed |
| US-4038479-A | AMINO PURINE DERIVATIVES | BURROUGHS WELLCOME CO. (US) | 1977-07-26 | — | — | US | disclosed |