Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11236550 | 0.76 | SLC6A4 (0.56) | SLC6A4HRH3SLC6A2CHRM2SCN1A | |
| SCHEMBL10779085 | 0.75 | CTSA (0.49) | — | |
| SCHEMBL7158810 | 0.75 | SLC6A4 (0.73) | SLC6A4HRH3SLC6A2HTR2AHRH1 | |
| SCHEMBL11239618 | 0.74 | SLC6A4 (0.68) | SLC6A4HRH3SLC6A2HTR2AHRH1 | |
| SCHEMBL11226530 | 0.73 | SLC6A4 (0.49) | SLC6A4HRH3SLC6A2CHRM2SCN1A | |
| SCHEMBL9019316 | 0.73 | PDPK1 (0.41) | ALDH1A1CYP3A4TSHRCYP2C19LMNA | |
| SCHEMBL15618287 | 0.71 | SLC6A4 (0.56) | SLC6A4HRH3SLC6A2CHRM2SCN1A | |
| SCHEMBL6729778 | 0.70 | SLC6A9 (0.64) | SLC6A4HRH3SLC6A2HTR2AHRH1 | |
| SCHEMBL5270870 | 0.70 | SLC6A4 (0.70) | SLC6A4HRH3SLC6A2HTR2AHRH1 | |
| SCHEMBL685134 | 0.70 | SLC6A4 (0.70) | SLC6A4HRH3SLC6A2HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4330546-A | 3-Aryl-3-aryloxypropylamines | JOHN WYETH & BROTHER LIMITED (GB) | 1982-05-18 | — | — | US | disclosed |