Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.68 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.50 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7158810 | 0.89 | SLC6A4 (0.73) | SLC6A4HRH3HTR2AHRH1SLC6A9 | |
| SCHEMBL5270870 | 0.83 | SLC6A4 (0.70) | SLC6A4HRH3HTR2AHRH1SLC6A9 | |
| SCHEMBL685134 | 0.83 | SLC6A4 (0.70) | SLC6A4HRH3HTR2AHRH1SLC6A9 | |
| SCHEMBL10913184 | 0.82 | SLC6A4 (0.68) | SLC6A4HRH3SLC6A9SLC6A2 | |
| SCHEMBL9500943 | 0.82 | SLC6A4 (0.68) | SLC6A4HRH3HTR2AHRH1SLC6A9 | |
| SCHEMBL4785426 | 0.82 | SLC6A4 (0.68) | SLC6A4HRH3HTR2AHRH1SLC6A9 | |
| SCHEMBL29700710 | 0.81 | SLC6A4 (1.00) | SLC6A4HRH3HTR2AHRH1SLC6A9 | |
| SCHEMBL679320 | 0.81 | SLC6A4 (1.00) | SLC6A4HRH3HTR2AHRH1SLC6A9 | |
| SCHEMBL9499401 | 0.79 | SLC6A4 (0.65) | SLC6A4HRH3SLC6A9SLC6A2 | |
| SCHEMBL4730810 | 0.79 | SLC6A4 (0.60) | SLC6A4HRH3HTR2AHRH1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4330546-A | 3-Aryl-3-aryloxypropylamines | JOHN WYETH & BROTHER LIMITED (GB) | 1982-05-18 | — | — | US | disclosed |