Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | CTSA | P10619 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11084533 | 0.78 | SMN1; SMN2 (0.42) | SLC6A3SMN1; SMN2LMNATSHRNPC1 | |
| SCHEMBL10779085 | 0.75 | CTSA (0.49) | CTSA | |
| SCHEMBL11228306 | 0.73 | SLC6A4 (0.49) | LMNATSHRRAB9AALDH1A1CYP3A4 | |
| SCHEMBL28307500 | 0.73 | SLC6A3 (0.40) | PDPK1SLC6A3LMNATSHROPRL1 | |
| SCHEMBL11821000 | 0.72 | LMNA (0.40) | SLC6A3SMN1; SMN2LMNATSHRNPC1 | |
| SCHEMBL557936 | 0.71 | ALOX5 (0.56) | PDPK1SLC6A3LMNATSHRCTSA | |
| SCHEMBL2110045 | 0.71 | TLR4 (0.49) | PDPK1SMN1; SMN2TSHRNPC1RAB9A | |
| SCHEMBL1367047 | 0.70 | — | — | |
| SCHEMBL2975785 | 0.69 | ALOX5 (0.43) | PDPK1SLC6A3LMNATSHRNR3C1 | |
| SCHEMBL18207227 | 0.68 | UGT2B7 (0.42) | SLC6A3NPC1RAB9AALDH1A1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576216-A | Universal standard reagents, method of preparing same and use thereof | Patchornik, Zipora (IL) | 1996-11-19 | — | — | US | disclosed |
| EP-0650595-A4 | UNIVERSAL STANDARD REAGENTS, METHOD OF PREPARING SAME AND USE THEREOF. | PATCHORNIK ZIPORA (IL) | 1996-08-21 | — | — | EP | disclosed |
| EP-0650595-A1 | UNIVERSAL STANDARD REAGENTS, METHOD OF PREPARING SAME AND USE THEREOF | PATCHORNIK, Zipora (IL) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994001771-A1 | UNIVERSAL STANDARD REAGENTS, METHOD OF PREPARING SAME AND USE THEREOF | PATCHORNIK, ZIPORA (IL) | 1994-01-20 | — | — | WO | disclosed |