Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 10/20 | 0.71 |
| ▸ | GPR34 | Q9UPC5 | 5/20 | 0.70 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.60 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.59 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.59 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.58 |
| ▸ | CDC25B | P30305 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | MME | P08473 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | CPA1 | P15085 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27658925 | 0.95 | GPR132 (0.79) | GPR132GPR34PTPN1CMKLR2CMKLR1 | |
| SCHEMBL1122875 | 0.95 | GPR132 (0.79) | GPR132GPR34PTPN1CMKLR2CMKLR1 | |
| SCHEMBL1123314 | 0.91 | GAA (0.64) | GPR132GPR34PTPN1MEN1LMNA | |
| SCHEMBL6029879 | 0.91 | GPR34 (0.77) | GPR132GPR34PTPN1MEN1LMNA | |
| SCHEMBL1123134 | 0.90 | GPR132 (0.71) | GPR132GPR34PTPN1CMKLR2CMKLR1 | |
| SCHEMBL1122846 | 0.90 | GPR132 (0.71) | GPR132GPR34PTPN1CMKLR2CMKLR1 | |
| SCHEMBL1123234 | 0.90 | GPR132 (0.71) | GPR132GPR34PTPN1CMKLR2CMKLR1 | |
| SCHEMBL1122680 | 0.89 | GPR132 (0.89) | GPR132GPR34PTPN1CMKLR2CMKLR1 | |
| SCHEMBL27638081 | 0.89 | GPR132 (0.89) | GPR132GPR34PTPN1CMKLR2CMKLR1 | |
| SCHEMBL5921650 | 0.89 | GPR132 (0.69) | GPR132GPR34PTPN1CMKLR2CMKLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| US-20060160894-A1 | Benzamides as ppar modulators | LABORATORIOS S.A.L.V.A.T.,S.A. (ES) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | PPARD, PPARA, PPARG | GPR132 122/4885GPR34 166/4885PTPN1 2708/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.