Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4046420 | 0.83 | TTR (0.49) | MAPTCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL4055160 | 0.82 | SMN1; SMN2 (0.40) | MAPTCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL28075538 | 0.77 | CYP3A4 (0.52) | ALOX5MAPTCYP3A4ABCG2ALDH1A1 | |
| SCHEMBL6794871 | 0.76 | ALOX15 (0.50) | ALOX5MAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11225857 | 0.76 | ALDH1A1 (0.51) | MAPTSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL25299267 | 0.75 | NPC1 (0.56) | SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL11220527 | 0.75 | NCEH1 (0.46) | MAPTCYP1A2CYP3A4CYP2C19SMN1; SMN2 | |
| SCHEMBL21412681 | 0.74 | MAPT (0.50) | MAPTCYP3A4ABCG2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8973887 | 0.74 | SMN1; SMN2 (0.57) | CYP1A2CYP2C19SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL19122730 | 0.73 | PPARG (0.55) | MAPTCYP1A2CYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4363905-A | PHASE TRANSFER CATALYST | GENERAL ELECTRIC COMPANY (US) | 1982-12-14 | — | — | US | disclosed |
| US-4316981-A | Polycarbonate transesterification | GENERAL ELECTRIC COMPANY (US) | 1982-02-23 | — | — | US | disclosed |