Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | ACACB | O00763 | 6/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25299267 | 0.80 | NPC1 (0.56) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL12841591 | 0.79 | HTR1A (0.48) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL20079748 | 0.77 | LMNA (0.47) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| Bicarbonate SCHEMBL3431862 | 0.75 | PNMT (0.52) | SMN1; SMN2MAPTGAAALDH1A1CNR1 | |
| SCHEMBL11228541 | 0.75 | ALOX5 (0.45) | SMN1; SMN2MAPTTHRBALDH1A1CYP1A2 | |
| SCHEMBL2563160 | 0.74 | NPC1 (0.55) | NPC1RAB9ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL22783730 | 0.73 | KCNH2 (0.44) | SMN1; SMN2MAPTALDH1A1CNR1CNR2 | |
| SCHEMBL8225538 | 0.73 | PGK1 (0.46) | SMN1; SMN2CNR1CNR2 | |
| SCHEMBL9588895 | 0.72 | TRPV1 (0.60) | NCEH1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL27902483 | 0.72 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2MAPTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329443-A | Process for polyester-carbonate transesterifications | GENERAL ELECTRIC COMPANY (US) | 1982-05-11 | — | — | US | disclosed |
| US-4321356-A | Transesterification process utilizing as a reactant bis(ortho-haloaryl)carbonates | GENERAL ELECTRIC COMPANY (US) | 1982-03-23 | — | — | US | disclosed |