Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 4/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244078 | 0.90 | MEN1 (0.36) | CNR2NOX1GHSRMAPTALDH1A1 | |
| SCHEMBL11244546 | 0.88 | CNR2 (0.41) | CNR2NOX1EDNRBEDNRAEGLN1 | |
| SCHEMBL11243224 | 0.83 | ALDH1A1 (0.36) | TP53MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11235691 | 0.79 | CNR2 (0.36) | CNR2EGLN1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL11233667 | 0.77 | RPS6KA2 (0.37) | TP53MAPTPOLBSMN1; SMN2ALDH1A1 | |
| SCHEMBL11239963 | 0.77 | CNR2 (0.36) | CNR2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL11241799 | 0.77 | CNR2 (0.36) | CNR2TP53GHSRMAPTPSMB5 | |
| SCHEMBL11374754 | 0.77 | KMT2A (0.38) | NOX1GHSRMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL11228890 | 0.77 | KMT2A (0.36) | CNR2NOX1MAPTALDH1A1MEN1 | |
| SCHEMBL11382459 | 0.72 | CNR2 (0.39) | CNR2TP53MAPTPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337340-A | FROM DIPHENYLAMINES AND BENZOYL OR 3-INDOLYLCARBONYL PYRIDINE- OR PYRAZINECARBOXYLIC ACIDS | STERLING DRUG INC. (US) | 1982-06-29 | — | — | US | disclosed |
| US-4243250-A | FUROPYRIDINONES OR FUROPYRAZINONES AS COLOR FORMERS | STERLING DRUG INC. (US) | 1981-01-06 | — | — | US | disclosed |
| US-4211872-A | COLOR FORMERS | FREEDOM CHEMICAL COMPANY | 1980-07-08 | — | — | US | disclosed |