Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229012 | 1.00 | APP (0.47) | APPCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL11830250 | 0.84 | NFE2L2 (0.42) | CYP3A4MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8050356 | 0.83 | ALDH1A1 (0.48) | CYP3A4MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5317693 | 0.83 | ALDH1A1 (0.48) | CYP3A4MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28653578 | 0.81 | APP (0.47) | APPALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL28645173 | 0.81 | APP (0.47) | APPALDH1A1KDM4EPKMSMN1; SMN2 | |
| SCHEMBL7024673 | 0.80 | APP (0.58) | APPCYP3A4MEN1KMT2AALDH1A1 | |
| SCHEMBL28650880 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL28650877 | 0.80 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL5960780 | 0.79 | APP (0.41) | APPCYP3A4MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015604-B1 | COMPOUNDS AND COMPOSITIONS FOR USE IN INHIBITION OF LIPOGENESIS IN MAMMALS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1983-02-23 | — | — | EP | disclosed |
| EP-0015604-A1 | Compounds and compositions for use in inhibition of lipogenesis in mammals | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1980-09-17 | — | — | EP | disclosed |
| US-4202902-A | VETERINARY MEDICINE | SHELL OIL COMPANY (US) | 1980-05-13 | — | — | US | disclosed |