Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29895231 | 1.00 | STAT3 (0.61) | STAT3KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL11229199 | 0.93 | KMT2A (0.56) | STAT3KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL10459763 | 0.93 | STAT3 (0.56) | STAT3KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL584246 | 0.91 | STAT3 (0.58) | STAT3KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL9442764 | 0.91 | LMNA (0.58) | STAT3KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL9186530 | 0.90 | LMNA (0.57) | STAT3KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL10766493 | 0.90 | STAT3 (0.54) | STAT3KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL5258333 | 0.90 | STAT3 (0.62) | STAT3KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL584797 | 0.89 | STAT3 (0.53) | STAT3KMT2ATDP1ALDH1A1KDM4E | |
| SCHEMBL10623495 | 0.89 | KMT2A (0.55) | STAT3KMT2ATDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703757-B | Synthesis method of melaxacin | 浙江中欣氟材股份有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-116283766-A | Cyanomethyl quinolone compound and preparation method and application thereof | 西南大学 | 2023-06-23 | — | — | CN | claimed |
| CN-115703757-A | Synthesis method of melafloxacin | 浙江中欣氟材股份有限公司 | 2023-02-17 | — | — | CN | claimed |
| CN-115636785-A | Quinolone cyanoacetate compounds and pharmaceutically acceptable salts thereof, and preparation method and application thereof | 西南大学 | 2023-01-24 | — | — | CN | claimed |
| CN-111208221-B | Method for detecting lomefloxacin hydrochloride related substances | 宜宾市南溪区红光制药有限公司 | 2022-07-05 | — | — | CN | claimed |
| CN-115636785-B | Quinolone cyanoacetate compound and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 西南大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-115703757-B | Synthesis method of melaxacin | 浙江中欣氟材股份有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-116283766-A | Cyanomethyl quinolone compound and preparation method and application thereof | 西南大学 | 2023-06-23 | — | — | CN | disclosed |
| CN-115703757-A | Synthesis method of melafloxacin | 浙江中欣氟材股份有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-115636785-A | Quinolone cyanoacetate compounds and pharmaceutically acceptable salts thereof, and preparation method and application thereof | 西南大学 | 2023-01-24 | — | — | CN | disclosed |
| CN-111208221-B | Method for detecting lomefloxacin hydrochloride related substances | 宜宾市南溪区红光制药有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-111208221-B | Method for detecting lomefloxacin hydrochloride related substances | 宜宾市南溪区红光制药有限公司 | 2022-07-05 | — | — | CN | disclosed |
| US-20040147545-A1 | Derivatives of oxazolidinones as antibacterial agents | LABORATORIOS VITA, S.A. (ES) | 2004-07-29 | — | — | US | disclosed |
| US-20030181719-A1 | Novel heterocyclic antibacterial compounds | MICROBIOTIX, INC. | 2003-09-25 | — | — | US | disclosed |
| US-6229017-B1 | BY ACYLATION AND CYCLIZATION OF A BENZOYL CHLORIDE OR NICOTINOYL CHLORIDE IN THE PRESENCE OF A NON-POLAR TO SLIGHTLY POLAR SOLVENT WITHOUT SEPARATION OF CHEMICAL INTERMEDIATES DURING PROCESS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-05-08 | — | — | US | disclosed |
| US-5753658-A | FOR TREATMENT OF BACTERIAL INFECTIONS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| EP-0610896-A1 | Quinolonecarboxylic acid derivatives as antibacterials | Senju Pharmaceutical Co., Ltd. (JP) | 1994-08-17 | — | — | EP | disclosed |
| EP-0140116-B1 | A 6-FLUORO-1,4-DIHYDRO-4-OXO-7-SUBSTITUTED PIPERAZINYL-QUINOLINE-3-CARBOXYLIC ACID DERIVATIVE AND THE METHOD FOR PREPARING THE SAME | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1988-05-25 | — | — | EP | disclosed |
| US-4528287-A | 6-Fluoro-1, 4-dihydro-4-oxo-7-substituted piperazinylquinoline-3-carboxylic acids and the method for preparing the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1985-07-09 | — | — | US | disclosed |
| EP-0140116-A1 | A 6-fluoro-1,4-dihydro-4-oxo-7-substituted piperazinyl-quinoline-3-carboxylic acid derivative and the method for preparing the same | Hokuriku Pharmaceutical Co.,Ltd (JP) | 1985-05-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181719-A1 | Novel heterocyclic antibacterial compounds | TOP1, TOP2A, TOP2B | STAT3 3898/4885KMT2A 2259/4885TDP1 74/4885 |
| US-20040147545-A1 | Derivatives of oxazolidinones as antibacterial agents | OXA1L, Q6ZSR9, PGC | STAT3 4244/4885KMT2A 3161/4885TDP1 4274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.