SCHEMBL11229232

SCHEMBL11229232

CCC1=CC(=O)C(OC)=CC1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERBB2 P04626 1/20 0.45
HKDC1 Q2TB90 2/20 0.42
ALOX5 P09917 13/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 2/20 0.40
TP53 P04637 2/20 0.40
CYP3A4 P08684 2/20 0.40
MAPT P10636 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 1/20 0.40
THRB P10828 1/20 0.40
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
BLM P54132 1/20 0.40
HSD17B10 Q99714 1/20 0.40
PTPN1 P18031 1/20 0.38
IDO1 P14902 1/20 0.38
CDC25A P30304 1/20 0.38
CDC25B P30305 1/20 0.38
USP2 O75604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10312241 0.81 ERBB2 (0.43) ERBB2HKDC1ALOX5KDM4EMEN1
SCHEMBL16520808 0.81 ERBB2 (0.43) ERBB2HKDC1ALOX5KDM4EMEN1
SCHEMBL49737 0.81 ERBB2 (0.62) ERBB2HKDC1ALOX5KDM4EMEN1
SCHEMBL10868487 0.81 STAT3 (0.42) PTPN1
SCHEMBL28856262 0.78 ERBB2 (0.59) ERBB2HKDC1ALOX5KDM4EMEN1
SCHEMBL28259188 0.78 ERBB2 (0.59) ERBB2HKDC1ALOX5KDM4EMEN1
SCHEMBL24071090 0.74 ALOX5 (0.45) ERBB2HKDC1ALOX5KDM4EMEN1
SCHEMBL10783378 0.74 TEK (0.59) ERBB2HKDC1ALOX5KDM4EMEN1
SCHEMBL19213933 0.72 ERBB2 (0.43) ERBB2HKDC1ALOX5
SCHEMBL3417111 0.70 HKDC1 (0.56) ERBB2HKDC1ALOX5KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4360469-A Preparation of quinones by salcomine-catalyzed oxidation of phenols EASTMAN KODAK COMPANY (US) 1982-11-23 US disclosed