Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227193 | 0.82 | ALDH1A1 (0.50) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL29236711 | 0.76 | LPAR3 (0.52) | TSHRHCAR2NAAAFDPSEPHX1 | |
| SCHEMBL29160716 | 0.76 | LPAR3 (0.52) | TSHRHCAR2NAAAFDPSEPHX1 | |
| SCHEMBL29160715 | 0.76 | LPAR3 (0.52) | TSHRHCAR2NAAAFDPSEPHX1 | |
| SCHEMBL9422342 | 0.73 | LMNA (0.43) | ALDH1A1CA1CA2TDP1L3MBTL1 | |
| SCHEMBL74371 | 0.73 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL8637991 | 0.73 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL10731279 | 0.73 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL5792770 | 0.73 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDHCAR2 | |
| SCHEMBL7412284 | 0.73 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4340599-A | Phosphono-hydroxy-acetic acid and its salts, their production and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1982-07-20 | — | — | US | disclosed |