SCHEMBL9422342

SCHEMBL9422342

COC(=O)C(O)P(=O)(OC)OC

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
CYP2C19 P33261 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.39
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA14 Q9ULX7 2/20 0.33
CA12 O43570 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KMT2A Q03164 1/20 0.31
MMP1 P03956 1/20 0.31
MMP2 P08253 1/20 0.31
MMP9 P14780 1/20 0.31
MMP8 P22894 1/20 0.31
CA9 Q16790 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8644884 0.77 LMNA (0.44) LMNACYP2C19TDP1
SCHEMBL10895290 0.77 SMN1; SMN2 (0.40) SMN1; SMN2CA1CA2CA14CA12
SCHEMBL9066687 0.77 SMN1; SMN2 (0.40) LMNACYP2C19SMN1; SMN2CA1CA2
SCHEMBL2978531 0.75 SMN1; SMN2 (0.41) LMNACYP2C19SMN1; SMN2CA1CA2
SCHEMBL2034964 0.73 SMN1; SMN2 (0.37) LMNACYP2C19SMN1; SMN2CA1CA2
SCHEMBL4087214 0.73 SMN1; SMN2 (0.37) LMNACYP2C19SMN1; SMN2CA1CA2
SCHEMBL2984783 0.73 SMN1; SMN2 (0.37) LMNACYP2C19SMN1; SMN2CA1CA2
SCHEMBL6101319 0.73 SMN1; SMN2 (0.37) LMNACYP2C19SMN1; SMN2CA1CA2
SCHEMBL11229249 0.73 ALDH1A1 (0.45) LMNACYP2C19SMN1; SMN2CA1CA2
SCHEMBL8228635 0.72 CYP2C19 (0.36) LMNACYP2C19SMN1; SMN2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6329690-A None JP disclosed
JP-H06329690-A PYRIMIDINE DERIVATIVE AND HERBICIDE COMPRISING THE SAME AS ACTIVE INGREDIENT MITSUBISHI PETROCHEM CO LTD 1994-11-29 JP disclosed