Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 4/20 | 0.56 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.56 |
| ▸ | ITGAL | P20701 | 4/20 | 0.56 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 1/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123375 | 0.90 | PPARG (0.65) | PPARGERAP2CA12CA1CA9 | |
| SCHEMBL1123056 | 0.90 | PPARG (0.54) | PPARGERAP2CA12CA1CA9 | |
| SCHEMBL27659071 | 0.86 | ERAP2 (0.59) | PPARGERAP2CA12CA1CA9 | |
| SCHEMBL1122844 | 0.83 | MEN1 (0.63) | PPARGERAP2KMT2AMEN1LNPEP | |
| SCHEMBL1122892 | 0.83 | PPARG (0.56) | PPARGERAP2KMT2AMEN1LNPEP | |
| SCHEMBL1122913 | 0.82 | PTPN1 (0.56) | PPARGCA12CA1CA9KMT2A | |
| SCHEMBL1122981 | 0.82 | ITGB2 (0.52) | PPARGERAP2ITGB2ICAM1ITGAL | |
| SCHEMBL1123050 | 0.81 | PTPN1 (0.69) | CA12CA1CA9PTPN1 | |
| SCHEMBL11873953 | 0.81 | KMT2A (0.73) | ERAP2CA12CA1CA9ITGB2 | |
| SCHEMBL1122735 | 0.81 | ADAM17 (0.51) | PPARGKMT2APTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |