Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.49 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.43 |
| ▸ | ITGAV | P06756 | 1/20 | 0.43 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123378 | 0.90 | GPR132 (0.57) | PTPN1ITGB3ITGA2BGPR132PTPN2 | |
| SCHEMBL1123050 | 0.87 | PTPN1 (0.69) | PTPN1ITGB3ITGA2BGPR132GAA | |
| SCHEMBL1122721 | 0.84 | PTPN1 (0.68) | PTPN1ITGB3ITGA2BGPR132GAA | |
| SCHEMBL1123437 | 0.83 | PTPN1 (0.67) | PTPN1ITGB3ITGA2BGPR132GAA | |
| SCHEMBL1122929 | 0.82 | PPARG (0.59) | PTPN1PPARGCA1CA12CA9 | |
| SCHEMBL1123517 | 0.82 | PTPN1 (0.64) | PTPN1ITGB3ITGA2BGPR132GAA | |
| SCHEMBL1123282 | 0.82 | PTPN1 (0.58) | PTPN1ITGB3ITGA2BGPR132GAA | |
| SCHEMBL1122735 | 0.81 | ADAM17 (0.51) | PTPN1ITGB3ITGA2BGPR132GAA | |
| SCHEMBL1123375 | 0.78 | PPARG (0.65) | PTPN1GPR132PPARGCA1CA12 | |
| SCHEMBL1123056 | 0.78 | PPARG (0.54) | PTPN1PPARGCA1CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |