Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | GPR132 | Q9UNW8 | 7/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.54 |
| ▸ | CCKBR | P32239 | 1/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | MMP14 | P50281 | 1/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.49 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.48 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123375 | 0.94 | PPARG (0.65) | MEN1KMT2APPARGGPR132HSP90AA1 | |
| SCHEMBL1122887 | 0.93 | TACR1 (0.54) | MEN1KMT2APPARGGPR132HSP90AA1 | |
| SCHEMBL1122981 | 0.91 | ITGB2 (0.52) | MEN1KMT2APPARGGPR132ADAM17 | |
| SCHEMBL1122892 | 0.87 | PPARG (0.56) | MEN1KMT2APPARGHSP90AA1HSP90AB1 | |
| SCHEMBL1123056 | 0.84 | PPARG (0.54) | MEN1KMT2APPARGADAM17MRGPRX4 | |
| SCHEMBL1122929 | 0.83 | PPARG (0.59) | MEN1KMT2APPARGMRGPRX4TACR1 | |
| SCHEMBL1123378 | 0.80 | GPR132 (0.57) | GPR132CMKLR2CMKLR1 | |
| SCHEMBL27635939 | 0.80 | PPARG (0.88) | MEN1KMT2APPARGGPR132HSP90AA1 | |
| SCHEMBL27635940 | 0.80 | PPARG (0.88) | MEN1KMT2APPARGGPR132HSP90AA1 | |
| SCHEMBL5921666 | 0.80 | MEN1 (0.67) | MEN1KMT2APPARGGPR132HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| CN-1835914-A | New benzamides as PPAR[upsilon] modulators | S A L V A T LAB SA (ES) | 2006-09-20 | — | — | CN | disclosed |
| US-20060160894-A1 | Benzamides as ppar modulators | LABORATORIOS S.A.L.V.A.T.,S.A. (ES) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | PPARD, PPARA, PPARG | MEN1 4877/4885KMT2A 1515/4885PPARG 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.