SCHEMBL11229628

SCHEMBL11229628

O=C(OS(=O)(=O)N(Cl)Br)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.45
F2 P00734 1/20 0.45
TSHR P16473 3/20 0.42
TDP1 Q9NUW8 3/20 0.39
TP53 P04637 2/20 0.39
KMT2A Q03164 4/20 0.38
ALDH1A1 P00352 4/20 0.38
MAPT P10636 3/20 0.38
MAPK1 P28482 1/20 0.38
HIF1A Q16665 1/20 0.38
POLB P06746 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A3 Q01959 1/20 0.38
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HSD17B10 Q99714 1/20 0.37
PKM P14618 1/20 0.37
NPC1 O15118 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5515237 0.78 TSHR (0.50) LMNAF2TSHRTDP1TP53
SCHEMBL2902948 0.75 LMNA (0.54) LMNAF2TSHRTDP1TP53
SCHEMBL1315543 0.74 LMNA (0.58) LMNAF2TSHRTDP1TP53
SCHEMBL2833087 0.74 LMNA (0.47) LMNAF2TSHRTDP1KMT2A
Hydrochloric Acid SCHEMBL3893489 0.73 LMNA (0.52) LMNAF2TSHRTDP1TP53
SCHEMBL29218970 0.73 LMNA (0.52) LMNAF2TSHRTDP1TP53
SCHEMBL4818821 0.72 LMNA (0.56) LMNAF2TSHRTDP1TP53
SCHEMBL11746011 0.72 LMNA (0.56) LMNAF2TSHRTDP1TP53
SCHEMBL27968908 0.71 LMNA (0.49) LMNAF2TSHRTDP1MAPT
SCHEMBL2539028 0.71 F2 (0.54) LMNAF2TSHRTDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4329431-A Instant culture media and method of sterilizing same YOUSSEF KAMAL A 1982-05-11 US disclosed