Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27968908 | 0.87 | LMNA (0.49) | LMNATSHRF2L3MBTL1SMN1; SMN2 | |
| SCHEMBL5515237 | 0.80 | TSHR (0.50) | LMNATSHRF2ALDH1A1L3MBTL1 | |
| SCHEMBL6234524 | 0.78 | LMNA (0.53) | LMNATSHRF2ALDH1A1KMT2A | |
| SCHEMBL27789868 | 0.75 | TAS2R14 (0.60) | — | |
| SCHEMBL28310222 | 0.74 | LMNA (0.53) | LMNATSHRF2ALDH1A1L3MBTL1 | |
| SCHEMBL11229628 | 0.74 | LMNA (0.45) | LMNATSHRF2ALDH1A1L3MBTL1 | |
| SCHEMBL9405232 | 0.74 | LMNA (0.49) | LMNATSHRF2ALDH1A1KMT2A | |
| SCHEMBL1020413 | 0.74 | TSHR (0.56) | LMNATSHRF2ALDH1A1L3MBTL1 | |
| SCHEMBL1315543 | 0.73 | LMNA (0.58) | LMNATSHRF2ALDH1A1KMT2A | |
| SCHEMBL27668297 | 0.72 | TSHR (0.54) | LMNATSHRF2ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010138955-A2 | METHODS AND COMPOSITIONS FOR TREATING NEOPLASIA | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-12-02 | — | — | WO | claimed |