Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197179 | 0.92 | ALDH1A1 (0.48) | ALDH1A1CYP1A2TSHRLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL11193716 | 0.91 | LMNA (0.48) | ALDH1A1CYP1A2TSHRLMNAKDM4E | |
| SCHEMBL422540 | 0.77 | ALDH1A1 (0.54) | ALDH1A1CYP1A2TSHRLMNAKDM4E | |
| SCHEMBL9595524 | 0.75 | ALDH1A1 (0.53) | ALDH1A1CYP1A2TSHRLMNAKDM4E | |
| SCHEMBL11399966 | 0.75 | ALDH1A1 (0.45) | ALDH1A1CYP1A2TSHRLMNAKDM4E | |
| SCHEMBL11188696 | 0.75 | MAPK1 (0.57) | ALDH1A1CYP1A2TSHRLMNAMAPK1 | |
| Hydrochloric Acid SCHEMBL9314574 | 0.74 | LMNA (0.45) | ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL11201404 | 0.74 | SYK (0.40) | ALDH1A1TSHRLMNAKDM4EMAPK1 | |
| SCHEMBL23132326 | 0.73 | ALDH1A1 (0.57) | ALDH1A1CYP1A2TSHRLMNAKDM4E | |
| SCHEMBL22922233 | 0.73 | ALDH1A1 (0.53) | ALDH1A1CYP1A2TSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4379158-A | Antisecretory imidazole amidine compounds, composition and method of use | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-04-05 | — | — | US | disclosed |
| US-4252819-A | ANTISECRETORY AGENTS; GASTRIC JUICE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-02-24 | — | — | US | disclosed |