Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144037 | 0.79 | KDM4E (0.50) | SCN4ACYP1A2CYP2C9KDM4EHIF1A | |
| SCHEMBL29863367 | 0.79 | KDM4E (0.50) | SCN4ACYP1A2CYP2C9KDM4EHIF1A | |
| SCHEMBL13777342 | 0.79 | TSHR (0.58) | SCN4ACYP1A2CYP2C9KDM4EHIF1A | |
| SCHEMBL11666766 | 0.78 | KDM4E (0.50) | CYP1A2CYP2C9KDM4EHIF1ATP53 | |
| SCHEMBL11383131 | 0.78 | SCN4A (0.53) | SCN4ACYP1A2CYP2C9KDM4EHIF1A | |
| SCHEMBL11284621 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL11284628 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL22135588 | 0.74 | KDM4E (0.64) | SCN4ACYP1A2CYP2C9KDM4EHIF1A | |
| SCHEMBL254428 | 0.74 | HPGD (0.53) | SCN4ACYP1A2CYP2C9KDM4EHIF1A | |
| SCHEMBL9665251 | 0.73 | SCN4A (0.51) | SCN4ACYP1A2CYP2C9KDM4EHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358309-A | NONPHYTOTOXIC | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1982-11-09 | — | — | US | disclosed |