Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SCN4A | P35499 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144037 | 1.00 | KDM4E (0.50) | KDM4ECYP1A2CYP2C9HIF1ATP53 | |
| SCHEMBL25267589 | 0.83 | KDM4E (0.58) | KDM4ECYP1A2CYP2C9HIF1ATP53 | |
| SCHEMBL13777342 | 0.82 | TSHR (0.58) | KDM4ECYP1A2CYP2C9HIF1ATP53 | |
| SCHEMBL2553310 | 0.81 | L3MBTL1 (0.45) | KDM4ETP53ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3736949 | 0.81 | TDP1 (0.56) | SMN1; SMN2HPGDTSHRGAAHTT | |
| SCHEMBL22557984 | 0.81 | KDM4E (0.57) | KDM4ECYP1A2CYP2C9HIF1ATP53 | |
| SCHEMBL11229698 | 0.79 | SCN4A (0.46) | KDM4ECYP1A2CYP2C9HIF1ATP53 | |
| SCHEMBL29863189 | 0.79 | MRGPRX4 (0.47) | CYP2C9ALDH1A1LMNAHPGDMEN1 | |
| SCHEMBL5000471 | 0.79 | KDM4E (0.48) | KDM4ETP53ALOX15ALDH1A1LMNA | |
| SCHEMBL3728298 | 0.78 | ALDH1A1 (0.49) | KDM4ECYP1A2CYP2C9TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143932-B | Piperazinone derivatives, process for producing the same, inhibitor, and method for controlling root-parasitic weeds | 南开大学 | 2022-09-16 | — | — | CN | disclosed |