Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.38 |
| ▸ | GABRD | O14764 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21206243 | 1.00 | OPRM1 (0.63) | OPRM1LMNATP53ALDH1A1TDP1 | |
| SCHEMBL22221856 | 0.97 | OPRM1 (0.60) | OPRM1LMNATP53ALDH1A1TDP1 | |
| SCHEMBL14006779 | 0.97 | OPRM1 (0.60) | OPRM1LMNATP53ALDH1A1TDP1 | |
| SCHEMBL22474102 | 0.97 | OPRM1 (0.60) | OPRM1LMNATP53ALDH1A1TDP1 | |
| SCHEMBL21142889 | 0.97 | OPRM1 (0.60) | OPRM1LMNATP53ALDH1A1TDP1 | |
| SCHEMBL19395998 | 0.97 | OPRM1 (0.60) | OPRM1LMNATP53ALDH1A1TDP1 | |
| SCHEMBL22221818 | 0.97 | OPRM1 (0.60) | OPRM1LMNATP53ALDH1A1TDP1 | |
| Octodrine SCHEMBL2253652 | 0.93 | — | — | |
| Octodrine SCHEMBL2248637 | 0.93 | — | — | |
| Octodrine SCHEMBL250416 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210332080-A1 | HYDROPHILIC LINKERS FOR ANTIBODY DRUG CONJUGATES | REGENERON PHARMACEUTICALS, INC. | 2021-10-28 | — | — | US | disclosed |
| WO-2021121327-A1 | SUBSTITUTED STRAIGHT CHAIN SPIRO DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |
| US-11034707-B2 | Group 5 metal complexes for catalytic amine functionalization | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2021-06-15 | — | — | US | disclosed |
| US-20200283459-A1 | GROUP 5 METAL COMPLEXES FOR CATALYTIC AMINE FUNCTIONALIZATION | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2020-09-10 | — | — | US | disclosed |
| EP-3403393-B1 | MULTI-APERTURE IMAGING DEVICES, METHOD FOR PRODUCING SAME, AND IMAGING SYSTEM | FRAUNHOFER GES FORSCHUNG (DE) | 2020-08-12 | — | — | EP | disclosed |
| WO-2020055976-A1 | TERT-BUTYL (S)-2-(4-(PHENYL)-6H-THIENO[3,2-F][1,2,4]TRIAZOLO[4,3-A] [1,4]DIAZEPIN-6-YL) ACETATE DERIVATIVES AND RELATED COMPOUNDS AS BROMODOMAIN BRD4 INHIBITORS FOR TREATING CANCER | GENENTECH, INC. (US) | 2020-03-19 | — | — | WO | disclosed |
| US-4312861-A | Pharmaceutical compositions containing N-alkyl-N-(nuclearly-substituted) benzylamines having vasotonia-regulating activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210332080-A1 | HYDROPHILIC LINKERS FOR ANTIBODY DRUG CONJUGATES | CD44, CD47, EPCAM | OPRM1 2765/4885LMNA 2253/4885TP53 968/4885 |
| US-20200283459-A1 | GROUP 5 METAL COMPLEXES FOR CATALYTIC AMINE FUNCTIONALIZATION | ADH5, PRMT5, MAOA | OPRM1 118/4885LMNA 3171/4885TP53 3774/4885 |
| US-11034707-B2 | Group 5 metal complexes for catalytic amine functionalization | ADH5, PRMT5, MAOA | OPRM1 118/4885LMNA 3171/4885TP53 3774/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.