Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229789 | 0.94 | NPC1 (0.47) | MRGPRX4RAB9ANPC1PKMHDAC7 | |
| SCHEMBL11227267 | 0.86 | HPGD (0.48) | RAB9ANPC1HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL11227264 | 0.80 | PTK2B (0.48) | HPGDSMN1; SMN2ALDH1A1KMT2AMAPT | |
| SCHEMBL11223714 | 0.79 | FABP3 (0.49) | MRGPRX4RAB9ANPC1PKMSMN1; SMN2 | |
| SCHEMBL11223717 | 0.78 | FABP4 (0.52) | MRGPRX4RAB9ANPC1PKMHPGD | |
| SCHEMBL10500437 | 0.78 | MRGPRX4 (0.53) | MRGPRX4RAB9ANPC1PKMHPGD | |
| SCHEMBL7916728 | 0.76 | MAPT (0.48) | HPGDSMN1; SMN2ALDH1A1LMNAALOX15 | |
| SCHEMBL9558840 | 0.75 | TTR (0.52) | MRGPRX4RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL9645037 | 0.74 | ESR1 (0.44) | MRGPRX4RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL8198688 | 0.74 | HDAC7 (0.59) | RAB9AHDAC7HPGDSMN1; SMN2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4329443-A | Process for polyester-carbonate transesterifications | GENERAL ELECTRIC COMPANY (US) | 1982-05-11 | — | — | US | disclosed |