Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27699387 | 0.82 | CES2 (0.54) | ALOX5CES2CES1AKR1B1NPC1 | |
| SCHEMBL11224650 | 0.81 | KMT2A (0.62) | ALOX5NPC1RAB9ACA12CA9 | |
| SCHEMBL339507 | 0.79 | CES2 (0.56) | ALOX5CES2CES1AKR1B1NPC1 | |
| SCHEMBL11226803 | 0.79 | ALOX5 (0.61) | ALOX5NPC1RAB9AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL68638 | 0.78 | CES2 (0.54) | ALOX5CES2CES1AKR1B1NPC1 | |
| SCHEMBL2948755 | 0.78 | ALOX5 (0.72) | ALOX5CES2CES1AKR1B1NPC1 | |
| SCHEMBL15477428 | 0.76 | CES2 (0.52) | ALOX5CES2CES1AKR1B1NPC1 | |
| SCHEMBL4430452 | 0.76 | CES2 (0.52) | ALOX5CES2CES1AKR1B1NPC1 | |
| SCHEMBL1516137 | 0.74 | NPC1 (0.75) | NPC1RAB9ACA12CA9TRPM8 | |
| SCHEMBL8263373 | 0.74 | ALDH1A1 (0.58) | ALOX5CES2CES1AKR1B1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4312982-A | BACTERICIDES | BEECHAM GROUP LIMITED (GB) | 1982-01-26 | — | — | US | disclosed |