Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5144207 | 0.81 | LMNA (0.44) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| Iodide SCHEMBL11214733 | 0.79 | LMNA (0.42) | ALDH1A1KDM4EHPGDMAPTTSHR | |
| SCHEMBL2221653 | 0.79 | MDM2 (0.48) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL14830566 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KDM4EHDAC1HDAC6HDAC3 | |
| Bromide SCHEMBL2356766 | 0.77 | MDM2 (0.47) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| Iodide SCHEMBL2353850 | 0.77 | MDM2 (0.47) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| Hydrochloric Acid SCHEMBL2356480 | 0.77 | MDM2 (0.47) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| Water SCHEMBL16320768 | 0.77 | MDM2 (0.47) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL11122619 | 0.77 | ALDH1A1 (0.49) | ALDH1A1HDAC1HDAC6HDAC3HDAC4 | |
| SCHEMBL11583186 | 0.75 | ALDH1A1 (0.50) | ALDH1A1KDM4EHDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57138399-A | — | — | None | — | — | JP | disclosed |
| JP-S57138399-A | MEASUREMENT OF ENZYME ACTIVITY | FUJIREBIO INC | 1982-08-26 | — | — | JP | disclosed |