Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 4/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA7 | P43166 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL11214733 | 0.98 | LMNA (0.42) | LMNAHSD17B10PDPK1ESR1ESR2 | |
| SCHEMBL11022263 | 0.88 | LIG1 (0.49) | LMNAHSD17B10PDPK1MAPTHPGD | |
| SCHEMBL2221653 | 0.83 | MDM2 (0.48) | LMNAMAPTHPGDHTTSLC6A2 | |
| Bromide SCHEMBL2356766 | 0.81 | MDM2 (0.47) | LMNAMAPTHPGDHTTSLC6A2 | |
| Hydrochloric Acid SCHEMBL2356480 | 0.81 | MDM2 (0.47) | LMNAMAPTHPGDHTTSLC6A2 | |
| Water SCHEMBL16320768 | 0.81 | MDM2 (0.47) | LMNAMAPTHPGDHTTSLC6A2 | |
| Iodide SCHEMBL2353850 | 0.81 | MDM2 (0.47) | LMNAMAPTHPGDHTTSLC6A2 | |
| SCHEMBL9635153 | 0.81 | CA5A (0.42) | LMNAMAPTCA12CA1CA2 | |
| SCHEMBL11122619 | 0.81 | ALDH1A1 (0.49) | LMNAHTTSLC6A2SLC6A3CA1 | |
| SCHEMBL11021523 | 0.81 | KDM4E (0.56) | MAPTSLC6A2SLC6A3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4565780-A | ENZYMATIC HYDROLYSIS OR A P-HYDROXYBENZOYL CHOLINE IN THE PRESENCEOF REDUCED NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE; LIVER DISORERS | SHINO-TEST LABORATORY CO., LTD. (JP) | 1986-01-21 | — | — | US | claimed |
| EP-0060059-B1 | METHOD FOR DETERMINING THE ACTIVITY OF CHOLINESTERASE AND DIAGNOSTIC SOLUTION FOR USE THEREIN | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1985-08-21 | — | — | EP | claimed |
| EP-0067234-B1 | METHOD FOR ASSAYING CHOLINESTERASE ACTIVITY | SHINO-TEST LABORATORY CO., LTD. (JP) | 1985-04-17 | — | — | EP | claimed |
| EP-0067234-A1 | METHOD FOR ASSAYING CHOLINESTERASE ACTIVITY | SHINO-TEST LABORATORY CO., LTD. (JP) | 1982-12-22 | — | — | EP | claimed |
| JP-58152500-A | — | — | None | — | — | JP | disclosed |
| CN-120161191-A | Marker composition for colorectal cancer detection and application thereof | 上海百趣生物医学科技有限公司 | 2025-06-17 | — | — | CN | disclosed |
| CN-116183889-A | Marker composition for colorectal cancer detection and application thereof | 上海百趣生物医学科技有限公司 | 2023-05-30 | — | — | CN | disclosed |
| US-20220128556-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-04-28 | — | — | US | disclosed |
| EP-3947743-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2022-02-09 | — | — | EP | disclosed |
| WO-2020201457-A1 | METHODS OF DIAGNOSING DISEASE | 4D Pharma Cork Limited (IE) | 2020-10-08 | — | — | WO | disclosed |
| EP-1283902-A4 | ASSAY FOR DETECTING, MEASURING AND MONITORING THE ACTIVITIES AND CONCENTRATIONS OF PROTEINS AND METHODS OF USE THEREOF | US ARMY MEDICAL RES AND MATERI (US) | 2007-05-02 | — | — | EP | disclosed |
| US-20040152145-A1 | Assay for detecting, measuring and monitoring the activities and concentrations of proteins and methods of use thereof | FEASTER SHAWN R (US) | 2004-08-05 | — | — | US | disclosed |
| US-4565780-A | ENZYMATIC HYDROLYSIS OR A P-HYDROXYBENZOYL CHOLINE IN THE PRESENCEOF REDUCED NICOTINAMIDE-ADENINE DINUCLEOTIDE PHOSPHATE; LIVER DISORERS | SHINO-TEST LABORATORY CO., LTD. (JP) | 1986-01-21 | — | — | US | disclosed |
| EP-0160980-A2 | Novel method for determining cholinesterase activity | NITTO BOSEKI CO., LTD. (JP) | 1985-11-13 | — | — | EP | disclosed |
| EP-0155825-A2 | Novel choline derivatives | NITTO BOSEKI CO., LTD. (JP) | 1985-09-25 | — | — | EP | disclosed |
| EP-0060059-B1 | METHOD FOR DETERMINING THE ACTIVITY OF CHOLINESTERASE AND DIAGNOSTIC SOLUTION FOR USE THEREIN | FUJIREBIO KABUSHIKI KAISHA also trading as FUJIREBIO INC. (JP) | 1985-08-21 | — | — | EP | disclosed |
| EP-0067234-B1 | METHOD FOR ASSAYING CHOLINESTERASE ACTIVITY | SHINO-TEST LABORATORY CO., LTD. (JP) | 1985-04-17 | — | — | EP | disclosed |
| JP-S58152500-A | ACTIVITY MEASUREMENT OF CHOLINESTERASE | SHINOTESUTO KENKYUSHO:KK | 1983-09-10 | — | — | JP | disclosed |
| EP-0067234-A1 | METHOD FOR ASSAYING CHOLINESTERASE ACTIVITY | SHINO-TEST LABORATORY CO., LTD. (JP) | 1982-12-22 | — | — | EP | disclosed |
| EP-0067234-A1 | METHOD FOR ASSAYING CHOLINESTERASE ACTIVITY | SHINO-TEST LABORATORY CO., LTD. (JP) | 1982-12-22 | — | — | EP | disclosed |