Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6520384 | 0.85 | NR4A2 (0.71) | CYSLTR1NR4A2NR4A1NR4A3PLA2G4B | |
| SCHEMBL1123058 | 0.85 | MAPT (0.62) | PPARGPPARDPPARA | |
| SCHEMBL5390756 | 0.84 | PKM (0.73) | PKMNR4A2NR4A1NR4A3FFAR1 | |
| SCHEMBL4327125 | 0.84 | PKM (0.73) | PKMNR4A2NR4A1NR4A3FFAR1 | |
| SCHEMBL832672 | 0.83 | MEN1 (0.53) | CYSLTR1FFAR1NR1H4CYP1A2 | |
| SCHEMBL6381840 | 0.83 | PPARG (0.68) | FFAR1CYP1A2PPARGPPARDPPARA | |
| SCHEMBL9043489 | 0.82 | CYP1A2 (0.55) | PKMCYSLTR1FFAR1PLA2G4BCYP1A2 | |
| SCHEMBL9558671 | 0.79 | PLA2G4B (0.55) | PKMCYSLTR1FFAR1NR1H4PLA2G4B | |
| SCHEMBL14967365 | 0.78 | NR4A2 (0.73) | PKMNR4A2NR4A1NR4A3FFAR1 | |
| SCHEMBL19849755 | 0.78 | PKM (0.59) | PKMCYSLTR1MRGPRX4PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |
| US-20060160894-A1 | Benzamides as ppar modulators | LABORATORIOS S.A.L.V.A.T.,S.A. (ES) | 2006-07-20 | — | — | US | disclosed |
| EP-1644321-A2 | NEW BENZAMIDES AS PPATY MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-04-12 | — | — | EP | disclosed |
| WO-2004110983-A2 | NEW BENZAMIDES AS PPARϒ MODULATORS | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160894-A1 | Benzamides as ppar modulators | PPARD, PPARA, PPARG | PKM 1028/4885CYSLTR1 311/4885NR4A2 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.