Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | THPO | P40225 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11230464 | 1.00 | LMNA (0.54) | LMNASLC6A4ADRA1AHRH1OPRK1 | |
| SCHEMBL11233121 | 0.74 | PPARG (0.45) | LMNAALDH1A1NFKB1KMT2ANPSR1 | |
| Triprolidine SCHEMBL3881294 | 0.70 | KMT2A (1.00) | LMNASLC6A4ADRA1AHRH1OPRK1 | |
| Triprolidine SCHEMBL29631820 | 0.70 | KMT2A (1.00) | LMNASLC6A4ADRA1AHRH1OPRK1 | |
| Triprolidine SCHEMBL4906 | 0.70 | KMT2A (1.00) | LMNASLC6A4ADRA1AHRH1OPRK1 | |
| Triprolidine SCHEMBL4905 | 0.70 | KMT2A (1.00) | LMNASLC6A4ADRA1AHRH1OPRK1 | |
| Triprolidine SCHEMBL1141100 | 0.70 | SLC6A4 (0.93) | LMNASLC6A4ADRA1AHRH1OPRK1 | |
| Triprolidine SCHEMBL42145 | 0.69 | LMNA (1.00) | LMNASLC6A4ADRA1AHRH1OPRK1 | |
| SCHEMBL11234661 | 0.69 | LMNA (0.61) | LMNASLC6A4ADRA1AHRH1OPRK1 | |
| Triprolidine SCHEMBL3273486 | 0.69 | KMT2A (0.97) | LMNASLC6A4ADRA1AHRH1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324792-A | SKIN DISORDERS, HAY FEVER, ASTHMA | GLAXO GROUP LIMITED (GB) | 1982-04-13 | — | — | US | disclosed |