Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11233228 | 0.88 | ALDH1A1 (0.43) | PPARGPPARACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2719494 | 0.77 | PPARG (0.51) | PPARGPPARACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL11230485 | 0.74 | LMNA (0.54) | PPARGPPARAALDH1A1LMNANPSR1 | |
| SCHEMBL11230464 | 0.74 | LMNA (0.54) | PPARGPPARAALDH1A1LMNANPSR1 | |
| SCHEMBL27265900 | 0.73 | ALDH1A1 (0.40) | PPARGPPARACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6579557 | 0.72 | RAB9A (0.39) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11669666 | 0.69 | LDHA (0.47) | CYP3A4RAB9ANPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2513945 | 0.69 | KMT2A (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL30554031 | 0.69 | SMN1; SMN2 (0.58) | RAB9ANPC1SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL9498449 | 0.67 | SMN1; SMN2 (0.41) | CYP1A2CYP3A4CYP2C9PKMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4324792-A | SKIN DISORDERS, HAY FEVER, ASTHMA | GLAXO GROUP LIMITED (GB) | 1982-04-13 | — | — | US | disclosed |