Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL11230601 | 0.84 | CASP6 (0.50) | KAT6AHSD17B1HSD17B2SCN9ASCN5A | |
| SCHEMBL11576128 | 0.76 | CASP6 (0.41) | CASP6MEN1KMT2A | |
| SCHEMBL7822715 | 0.72 | HSD17B1 (0.42) | HSD17B1HSD17B2KDM4EMEN1KMT2A | |
| SCHEMBL7822719 | 0.72 | CYP1A2 (0.57) | HSD17B1HSD17B2HSD11B1KDM4EESR1 | |
| SCHEMBL10573506 | 0.70 | LMNA (0.63) | — | |
| SCHEMBL5381415 | 0.70 | CASP6 (0.42) | KAT6AHSD11B1CASP6PDPK1KDM4E | |
| SCHEMBL11245615 | 0.70 | PTPN1 (0.44) | HSD17B1HSD17B2KDM4EMEN1KMT2A | |
| SCHEMBL29599325 | 0.69 | KDM4E (0.53) | HSD11B1KDM4EMEN1KMT2AESR1 | |
| SCHEMBL1161290 | 0.69 | KDM4E (0.53) | HSD11B1KDM4EMEN1KMT2AESR1 | |
| SCHEMBL11744759 | 0.69 | HSD17B1 (0.38) | HSD17B1HSD17B2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4331613-A | Process for the preparation of trifluoromethylnaphthalenes | BAYER AKTIENGESELLSCHAFT (DE) | 1982-05-25 | — | — | US | disclosed |