SCHEMBL1123062

SCHEMBL1123062

CCCCCCCCCCCCCCCCCCCCCC.CO[Si](CCCN)(OC)OC

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.57
DNM1 Q05193 9/20 0.52
TSHR P16473 2/20 0.52
EPHX1 P07099 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
ALDH1A1 P00352 1/20 0.52
THRB P10828 1/20 0.36
HTR2A P28223 1/20 0.33
GNAI3 P08754 1/20 0.33
GNAO1 P09471 1/20 0.33
GNAI1 P63096 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexadecane SCHEMBL28823222 1.00 LMNA (0.57) LMNADNM1TSHREPHX1MEN1
SCHEMBL28823240 1.00 LMNA (0.57) LMNADNM1TSHREPHX1MEN1
Hexadecylamine SCHEMBL28110136 0.93 DNM1 (0.56) LMNADNM1TSHREPHX1MEN1
Ethylenediamine SCHEMBL20549871 0.91 LMNA (0.57) LMNADNM1TSHREPHX1MEN1
Butane SCHEMBL28669029 0.91 LMNA (0.45) LMNADNM1TSHREPHX1MEN1
SCHEMBL7865530 0.90 LMNA (0.49) LMNADNM1TSHREPHX1MEN1
SCHEMBL7043475 0.90 LMNA (0.49) LMNADNM1TSHREPHX1MEN1
SCHEMBL29140673 0.89 DNM1 (0.56) LMNADNM1TSHREPHX1MEN1
Octadecylamine SCHEMBL9551514 0.89 DNM1 (0.56) LMNADNM1TSHREPHX1MEN1
SCHEMBL28541903 0.88 LMNA (0.44) LMNADNM1TSHREPHX1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1997873-B1 Thickened surfactant-free cleasing and multifunctional liquid coating compositions containing nonreactive abrasive solid particles and an organosilane quaternary compound and methods of using RESOURCE DEV LLC (US) 2011-02-09 EP claimed