Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.34 |
| ▸ | RARG | P13631 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL571115 | 0.81 | MAPT (0.45) | LMNANPC1RAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL28672526 | 0.81 | ALOX5 (0.46) | LMNAALOX5NISCHMAPTALDH1A1 | |
| SCHEMBL230113 | 0.79 | NISCH (0.53) | LMNANPC1RAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL29518399 | 0.79 | NISCH (0.53) | LMNANPC1RAB9ASMN1; SMN2ALOX5 | |
| SCHEMBL11240988 | 0.77 | CYP11B1 (0.41) | ALOX5NISCHMAPTKDM4EALDH1A1 | |
| SCHEMBL616344 | 0.72 | RARA (0.46) | RAB9AALOX5NISCHMAPTALDH1A1 | |
| SCHEMBL28663649 | 0.70 | MEN1 (0.50) | LMNANPC1RAB9ASMN1; SMN2MAOA | |
| SCHEMBL28668688 | 0.70 | ALOX5 (0.45) | LMNAALOX5MAPTTDP1CYP3A4 | |
| SCHEMBL2070069 | 0.67 | MAPT (0.50) | LMNANPC1RAB9ASMN1; SMN2ALOX5 | |
| Biphenyl SCHEMBL27625903 | 0.67 | ADORA1 (0.55) | LMNANPC1RAB9ASMN1; SMN2MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341792-A | ANTIDIABETIC AND CARDIOTONIC AGENTS | PFIZER INC. (US) | 1982-07-27 | — | — | US | disclosed |