SCHEMBL11230869

SCHEMBL11230869

CNC(=O)C(C(=NO)n1cncn1)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.33
CYP26A1 O43174 2/20 0.33
LMNA P02545 2/20 0.33
NPC1 O15118 2/20 0.33
MAPT P10636 2/20 0.33
PKM P14618 2/20 0.33
HTT P42858 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MITF O75030 1/20 0.33
ATM Q13315 2/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
KMT2A Q03164 1/20 0.32
FAAH O00519 1/20 0.30
MGLL Q99685 1/20 0.30
TP53 P04637 1/20 0.30
POLB P06746 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11233549 0.86 CYP26A1 (0.31) RAB9ACYP26A1LMNANPC1MAPT
SCHEMBL11241867 0.86 RAB9A (0.32) RAB9ACYP26A1LMNANPC1MAPT
SCHEMBL11235119 0.83 CYP26A1 (0.40) RAB9ACYP26A1LMNANPC1MAPT
SCHEMBL11237997 0.82 MEN1 (0.33) LMNAMAPTPKMSMN1; SMN2ATM
SCHEMBL11235925 0.76
SCHEMBL11225659 0.76
SCHEMBL11233303 0.75 CYP26A1 (0.34) CYP26A1
SCHEMBL11239800 0.75 ELANE (0.41) LMNAKMT2A
SCHEMBL11240989 0.75 ELANE (0.38)
SCHEMBL11248332 0.75 KMT2A (0.32) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359469-A Combating pests with N-sulphenylated oxime-carbamates BAYER AKTIENGESELLSCHAFT (DE) 1982-11-16 US disclosed