Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26A1 | O43174 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MITF | O75030 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11241867 | 0.88 | RAB9A (0.32) | CYP26A1NPC1MITFMAPTPKM | |
| SCHEMBL11230869 | 0.86 | RAB9A (0.33) | CYP26A1NPC1MITFMAPTPKM | |
| SCHEMBL11235119 | 0.78 | CYP26A1 (0.40) | CYP26A1NPC1MITFMAPTPKM | |
| SCHEMBL11237997 | 0.74 | MEN1 (0.33) | MAPTPKMSMN1; SMN2LMNA | |
| SCHEMBL11660971 | 0.70 | — | — | |
| SCHEMBL11660976 | 0.70 | — | — | |
| SCHEMBL11234739 | 0.69 | FAAH (0.43) | CYP26A1MAPTPKMSMN1; SMN2LMNA | |
| SCHEMBL11261748 | 0.66 | — | — | |
| SCHEMBL11225659 | 0.66 | — | — | |
| SCHEMBL11240740 | 0.66 | ATM (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344953-A | INSECTICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | claimed |
| US-4344953-A | INSECTICIDES, NEMATOCIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-08-17 | — | — | US | disclosed |