SCHEMBL11237997

SCHEMBL11237997

CNC(=O)C(C(=NO)n1cncn1)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.31
HSP90AA1 P07900 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ATM Q13315 1/20 0.31
FAAH O00519 1/20 0.31
MGLL Q99685 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11230869 0.82 RAB9A (0.33) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL11245287 0.77 NOS1 (0.39)
SCHEMBL11234739 0.75 FAAH (0.43) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL11240740 0.74 ATM (0.35) MEN1KMT2AALDH1A1ATMFAAH
SCHEMBL11240738 0.74 ATM (0.35) MEN1KMT2AALDH1A1ATMFAAH
SCHEMBL11233549 0.74 CYP26A1 (0.31) LMNAMAPTPKMSMN1; SMN2
SCHEMBL11241867 0.74 RAB9A (0.32) LMNAMAPTPKMSMN1; SMN2ATM
SCHEMBL11235119 0.71 CYP26A1 (0.40) MEN1KMT2AALDH1A1LMNAHSP90AA1
SCHEMBL11240793 0.69 ATM (0.33) MEN1KMT2AATMFAAHMGLL
SCHEMBL14884967 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4359469-A Combating pests with N-sulphenylated oxime-carbamates BAYER AKTIENGESELLSCHAFT (DE) 1982-11-16 US disclosed