Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.47 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1123043 | 0.94 | BCHE (0.52) | SMPD1BCHEKMT2APTGESSLC2A1 | |
| SCHEMBL1123126 | 0.91 | BCHE (0.53) | SMPD1BCHEKMT2APTGESMAOB | |
| SCHEMBL1122938 | 0.87 | BCHE (0.55) | SMPD1BCHEKMT2APTGESMAOB | |
| SCHEMBL1123224 | 0.87 | BCHE (0.53) | BCHEKMT2ALPAR1 | |
| SCHEMBL1123087 | 0.85 | FFAR1 (0.56) | SMPD1BCHEKMT2APTGESSLC2A1 | |
| SCHEMBL1123023 | 0.83 | MAOB (0.53) | SMPD1BCHEKMT2APTGESMAOB | |
| SCHEMBL1123468 | 0.82 | KMT2A (0.54) | SMPD1KMT2APTGESMAOBNR4A2 | |
| SCHEMBL1122608 | 0.82 | FFAR1 (0.59) | SMPD1BCHEKMT2APTGESSLC2A1 | |
| SCHEMBL1123467 | 0.80 | NPC1 (0.55) | BCHEKMT2APTGESMAOBNR4A2 | |
| SCHEMBL1123406 | 0.80 | NR4A2 (0.56) | SMPD1KMT2APTGESMAOBNR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644321-B1 | NEW BENZAMIDES AS PPATY MODULATORS | S A L V A T LAB SA (ES) | 2011-02-09 | — | — | EP | disclosed |