Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 6/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11229748 | 0.93 | ALDH1A1 (0.39) | SIGMAR1DRD2OPRM1KCNH2ALDH1A1 | |
| SCHEMBL11228908 | 0.90 | SIGMAR1 (0.38) | SIGMAR1DRD2OPRM1KCNH2ALDH1A1 | |
| SCHEMBL11228036 | 0.89 | SIGMAR1 (0.52) | SIGMAR1DRD2OPRM1KCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11374967 | 0.86 | ALDH1A1 (0.38) | SIGMAR1DRD2OPRM1ALDH1A1LTA4H | |
| SCHEMBL18719633 | 0.84 | SIGMAR1 (0.55) | SIGMAR1DRD2OPRM1KCNH2LMNA | |
| SCHEMBL11222563 | 0.81 | SIGMAR1 (0.44) | SIGMAR1DRD2OPRM1ALDH1A1LMNA | |
| SCHEMBL11360418 | 0.81 | ALDH1A1 (0.40) | SIGMAR1DRD2OPRM1KCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11363026 | 0.81 | ALDH1A1 (0.37) | DRD2ALDH1A1LTA4HLMNAMAPT | |
| Hydrochloric Acid SCHEMBL11375168 | 0.81 | ALDH1A1 (0.41) | SIGMAR1DRD2OPRM1KCNH2ALDH1A1 | |
| SCHEMBL11370945 | 0.79 | LTA4H (0.41) | SIGMAR1DRD2OPRM1KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353901-A | HYPERTENSION, CONGESTIVE HEART FAILURE, ARRHYTHMIAMIGRAINE, VASOSPASTIC DISORDERS, ASTHMA | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |