Pentachlorophenol

Pentachlorophenol

SCHEMBL9501530

OCC(O)C(O)CO.OP(O)O.Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.48
CYP2C9 P11712 4/20 0.48
TSHR P16473 3/20 0.48
HIF1A Q16665 3/20 0.48
HPGD P15428 2/20 0.48
HSD17B10 Q99714 2/20 0.48
LMNA P02545 2/20 0.48
MEN1 O00255 1/20 0.48
ALDH1A1 P00352 1/20 0.48
MAPT P10636 1/20 0.48
KMT2A Q03164 1/20 0.48
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.38
CYP2C19 P33261 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentachlorophenol SCHEMBL164440 0.93 TSHR (0.56) CYP1A2CYP2C9TSHRHIF1AHPGD
Pentachlorophenol SCHEMBL18039457 0.86 CYP1A2 (0.48) CYP1A2CYP2C9TSHRHIF1AHPGD
Pentachlorophenol SCHEMBL9362639 0.86 CYP1A2 (0.48) CYP1A2CYP2C9TSHRHIF1AHPGD
Lindane SCHEMBL7913369 0.84 CYP1A2 (0.46) CYP1A2CYP2C9TSHRHIF1AHPGD
Pentachlorophenol SCHEMBL10591497 0.84 CYP1A2 (0.52) CYP1A2CYP2C9TSHRHIF1AHPGD
Mannitol SCHEMBL11230894 0.83 LMNA (0.55) CYP1A2CYP2C9TSHRHIF1AHPGD
Pentachlorophenol SCHEMBL11235831 0.83 TSHR (0.50) CYP1A2CYP2C9TSHRHIF1AHPGD
Sorbitol SCHEMBL2688276 0.83 LMNA (0.55) CYP1A2CYP2C9TSHRHIF1AHPGD
Pentachlorophenol SCHEMBL11027712 0.77 TSHR (0.61) CYP1A2CYP2C9TSHRHIF1AHPGD
Pentachlorophenol SCHEMBL10579546 0.77 CYP1A2 (0.41) CYP1A2CYP2C9TSHRHIF1AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0548293-A1 THERMOOXIDATIVE STABILIZATION OF POLYOLEFINS WITH AN OXO-PIPERAZINYL-TRIAZINE AND A PHOSPHOROUS ACID ESTER THE B.F. GOODRICH COMPANY (US) 1993-06-30 EP disclosed