Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11221152 | 0.96 | MTNR1A (0.48) | MTNR1AHTR2AHTR7POLBHRH3 | |
| SCHEMBL11238161 | 0.88 | DRD2 (0.36) | HTR2AHTR7DRD2 | |
| SCHEMBL11227155 | 0.86 | CA2 (0.40) | HTR2AHTR7FFAR1DRD2 | |
| SCHEMBL11218554 | 0.86 | DRD2 (0.34) | MTNR1AHTR2AHTR7LRRK2DRD2 | |
| SCHEMBL11220552 | 0.85 | DRD2 (0.47) | HTR2AHTR7DRD2 | |
| SCHEMBL11224531 | 0.84 | CA2 (0.40) | HTR2AHTR7DRD2 | |
| Hydrochloric Acid SCHEMBL11226124 | 0.84 | DRD2 (0.46) | HTR2AHTR7DRD2 | |
| SCHEMBL11234746 | 0.83 | CA2 (0.40) | HTR2AHTR7FFAR1DRD2 | |
| SCHEMBL11224382 | 0.82 | HTR2A (0.37) | MTNR1AHTR2ALRRK2DRD2 | |
| SCHEMBL11233485 | 0.79 | DRD2 (0.45) | HTR2AHTR7DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353901-A | HYPERTENSION, CONGESTIVE HEART FAILURE, ARRHYTHMIAMIGRAINE, VASOSPASTIC DISORDERS, ASTHMA | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |