Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.48 |
| ▸ | GBA1 | P04062 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 4/20 | 0.42 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11231387 | 0.92 | GBA1 (0.50) | NAMPTSLC6A4GBA1IDO1KDM1A | |
| Hydrochloric Acid SCHEMBL11232679 | 0.91 | IDO1 (0.50) | NAMPTSLC6A4GBA1IDO1KDM1A | |
| SCHEMBL9636847 | 0.81 | GBA1 (0.50) | SLC6A4GBA1KDM1AKDM1BMAOA | |
| SCHEMBL28259865 | 0.78 | NAMPT (0.41) | NAMPTSLC6A4GBA1KDM1AKDM1B | |
| SCHEMBL11232133 | 0.77 | BCHE (0.48) | NAMPTSLC6A4 | |
| SCHEMBL237382 | 0.77 | ITGB3 (0.47) | NAMPTSLC6A4GBA1HRH3 | |
| Hydrochloric Acid SCHEMBL11229034 | 0.76 | BCHE (0.47) | NAMPTSLC6A4KDM1AKDM1B | |
| Hydrochloric Acid SCHEMBL10840761 | 0.75 | ITGB3 (0.46) | NAMPTSLC6A4GBA1HRH3 | |
| SCHEMBL8097693 | 0.75 | ITGB3 (0.46) | NAMPTSLC6A4GBA1HRH3 | |
| SCHEMBL82734 | 0.74 | GBA1 (0.61) | SLC6A4GBA1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4357337-A | PIPERIDINYLALKYL DERIVATIVES | PHARMINDUSTRIE (FR) | 1982-11-02 | — | — | US | disclosed |