SCHEMBL82734

SCHEMBL82734

c1ccc(CCCC2CCNCC2)cc1

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 1/20 0.61
SLC6A4 P31645 2/20 0.55
SIGMAR1 Q99720 1/20 0.50
SLC18A3 Q16572 1/20 0.50
ITGB3 P05106 1/20 0.49
ITGA2B P08514 1/20 0.49
HRH3 Q9Y5N1 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7669421 0.98 GBA1 (0.59) GBA1SLC6A4SIGMAR1SLC18A3ITGB3
SCHEMBL3358034 0.95 GBA1 (0.59) GBA1SLC6A4SIGMAR1ITGB3ITGA2B
SCHEMBL11537058 0.93 GBA1 (0.58) GBA1SLC6A4SIGMAR1ITGB3ITGA2B
SCHEMBL2241250 0.89 GBA1 (0.66) GBA1SLC6A4
Hydrochloric Acid SCHEMBL1532936 0.87 GBA1 (0.63) GBA1SLC6A4
SCHEMBL31490479 0.86 SLC18A3 (0.57) SLC18A3HRH3
SCHEMBL12735855 0.85 MEN1 (0.59) GBA1SIGMAR1ITGB3ITGA2BHRH3
Hydrochloric Acid SCHEMBL1532763 0.84 MEN1 (0.57) GBA1SIGMAR1ITGB3ITGA2BHRH3
SCHEMBL7103234 0.82 SLC18A3 (0.62) SIGMAR1SLC18A3
SCHEMBL26629763 0.82 SLC18A3 (0.58) SIGMAR1SLC18A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260117393-A1 ETCHING AGENT COMPOSITION AND ETCHING METHOD USING THE SAME KCTECH CO., LTD. (KR) 2026-04-30 US claimed
CN-116768826-B Rupestonic acid amide derivative containing nitrogen heterocycle, and preparation method and application thereof 中国科学院新疆理化技术研究所 2025-05-27 CN claimed
CN-115466189-B Purification method of amino acid and derivative thereof 安徽普利药业有限公司 2024-08-30 CN claimed
CN-116768826-A Rupestonic acid amide derivative containing nitrogen heterocycle, and preparation method and application thereof 中国科学院新疆理化技术研究所 2023-09-19 CN claimed
CN-115466189-A Preparation and purification method of amino acid and derivatives thereof 安徽普利药业有限公司 2022-12-13 CN claimed
EP-0012643-B1 1-PHENYL-3-(4-PIPERIDYL)-PROPAN-1-ONE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, AND MEDICAMENTS CONTAINING THEM PHARMUKA LABORATOIRES (FR) 1982-02-17 EP claimed
US-4294841-A ANTIARRHYTHMIA AGENTS PHARMINDUSTRIE (FR) 1981-10-13 US claimed
US-3983107-A ARTERIOSCLEROSIS PFIZER INC. (US) 1976-09-28 US claimed
US-12637494-B2 Method for producing peptide containing non-natural amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2026-05-26 US disclosed
US-20260117393-A1 ETCHING AGENT COMPOSITION AND ETCHING METHOD USING THE SAME KCTECH CO., LTD. (KR) 2026-04-30 US disclosed
US-12410212-B2 Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-09 US disclosed
US-12404299-B2 Method for producing peptide compound comprising highly sterically hindered amino acid CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-09-02 US disclosed
EP-4603105-A1 PHARMACEUTICAL COMPOSITION CONTAINING CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT AGAINST HRAS AND NRAS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-20 EP disclosed
EP-4592308-A1 CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-07-30 EP disclosed
US-4136180-A HYPOLIPIDEMIC SUBSTITUTED STYRENESULFONYLUREAS PFIZER INC. (US) 1979-01-23 US disclosed
US-4077958-A ANTIDEPRESSANTS E. R. SQUIBB & SONS, INC. (US) 1978-03-07 US disclosed
US-4062960-A Hypolipidemic alkenesulfonamides PFIZER INC. (US) 1977-12-13 US disclosed
US-4007191-A ANTIDEPRESSANT E. R. SQUIBB & SONS, INC. (US) 1977-02-08 US disclosed
US-3983107-A ARTERIOSCLEROSIS PFIZER INC. (US) 1976-09-28 US disclosed
US-3935227-A ANTIDEPRESSANTS, ANTIANXIETY, ANTIINFLAMMATORY AGENTS E. R. SQUIBB & SONS, INC. (US) 1976-01-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637494-B2 Method for producing peptide containing non-natural amino acid MRPL21, RPL21, RPL30 GBA1 4499/4885SLC6A4 4434/4885SIGMAR1 3101/4885
US-12410212-B2 Cyclic compound having selective KRAS inhibitory effect on HRAS and NRAS KRAS, HRAS, NRAS GBA1 4076/4885SLC6A4 4849/4885SIGMAR1 4837/4885
US-12404299-B2 Method for producing peptide compound comprising highly sterically hindered amino acid DNPEP, VIP, NPEPPS GBA1 2500/4885SLC6A4 2004/4885SIGMAR1 3154/4885
US-20260117393-A1 ETCHING AGENT COMPOSITION AND ETCHING METHOD USING THE SAME HCN4, HAO2, ASIC1 GBA1 2642/4885SLC6A4 665/4885SIGMAR1 728/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.